Establishment of a method for the determination of hydrogen sulfide in human serum by liquid chromatography-tandem mass spectrometry and evaluation of its clinical application  

作　　者：Chunyan Li Jia Chen Yu Su Wuzheng Liu Xiangyu Meng Ao Zhang Yitong Bai Yingzi Liu Ruichen Liu Lin Zhang Jun Wu 

机构地区：[1]Beijing Jishuitan Hospital,Capital Medical University,Beijing 100035,China [2]Department of Laboratory Medicine,Peking University Fourth School of Clinical Medicine,Beijing Jishuitan Hospital,Beijing 100035,China [3]Peking University,Beijing 100000,China [4]Shanghai AB Sciex Analytical Instrument Trading Co.,Ltd.,Shanghai 100027,China [5]Department of Geriatric Cardiology,the Second Medical Centre,Chinese PLA General Hospital,Beijing 100853,China

出　　处：《Acta Biochimica et Biophysica Sinica》2024年第3期494-498,共5页生物化学与生物物理学报（英文版）

基　　金：This work was supported by the grants from the Beijing Hospitals Authority Youth Programme(No.QMS20220405);the Beijing Jishuitan Hospital Nova Program(No.XKXX202212);the Beijing Municipal Health Commission(No.BJRITO-RDP-2023);the Beijing JST Research Funding(No.YGQ-202311).

摘　　要：Hydrogen sulfide(H2S)is an inorganic compound.It is a colorless,water-soluble gas that results in the smell of rotten eggs.Hydrogen sulfide is the third most important endogenous gas signaling molecule after nitric oxide,NO,and carbon monoxide(CO)[1].Hydrogen sulfide is involved in many physiological and pathological processes.Relevant studies have shown that hydrogen sulfide is widely distributed in the cardiovascular,nervous,digestive,endocrine,and immune systems.

关 键 词：COMPOUND SULFIDE MONOXIDE 

分 类 号：O64[理学—物理化学]