黄芩炭最佳炮制工艺的研究  

Study on the optimal concoction process of Scutellariae Radix Charcoal

作　　者：陈智[1] 马玉坤 李佳旭 CHEN Zhi;MA Yu-kun;LI Jia-xu(Shandong University of Traditional Chinese Medicine,Ji'nan,250355,China;Ji'nan Stomatological Hos-pital,Ji'nan,250118,China)

机构地区：[1]山东中医药大学,山东济南250355 [2]济南市口腔医院,山东济南250118

出　　处：《时珍国医国药》2024年第1期114-117,共4页Lishizhen Medicine and Materia Medica Research

基　　金：山东省自然科学基金面上项目(ZR2021MH009);山东省中医药科技项目(2021M143);国家中医药管理局中药炮制技术传承基地项目(国中医药科技中药[2022]59号)。

摘　　要：目的 优选黄芩炭的最佳炮制工艺。方法 在单因素实验基础上选取合适的实验因素水平并采用L_9(3~4)正交实验设计,以总黄酮含量及黄芩素含量为指标,优选出黄芩炭的最佳炮制工艺,并进行工艺验证。结果 黄芩炭的最佳炮制工艺为炮制温度220℃,炮制时间为12min,炮制时的翻炒频率为20次/min。结论 该实验优选出的黄芩炭最佳炮制工艺稳定可行,可为黄芩炭的质量控制提供参考。Objective To select the best preparation process for Scutellaria Radix Charcoal.Methods On the basis of single-factor experiments,the appropriate level of experimental factors was selected and L9(34)orthogonal experimental design was used,and the best processing process of Scutellaria Radix Charcoal was selected with total flavonoid content and baicalein content as reference,and verified.Results The optimum concoction process for Scutellaria Radix Charcoal was 220℃,the concoction time was 12 min,and the frequency of stir-frying was 20 times/min.Conclusion The best concoction process for Scutellaria Radix Charcoal selected in this experiment is stable and feasible,and can provide a reference for the quality control of Scutellaria Radix Charcoal.

关 键 词：黄芩炭 黄芩素 炮制工艺 质量控制 正交实验 

分 类 号：R283.3[医药卫生—中药学]