肥胖相关肿瘤研究进展  

Research progress of obesity-related tumors

作　　者：范晓轩 王娜[1] 朱丽花[2] 王亮[1] Fan Xiaoxuan;Wang Na;Zhu Lihua;Wang Liang(Department of Oncology,The First Affiliated Hospital of Jinan University,Guangzhou 510630,China)

机构地区：[1]暨南大学第一附属医院肿瘤科,广州510630 [2]暨南大学第一附属医院风湿免疫科,广州510630

出　　处：《中华肥胖与代谢病电子杂志》2023年第3期173-178,共6页Chinese Journal Of Obesity and Metabolic Diseases：Electronic Edition

基　　金：广州市基础研究计划市校联合资助项目(SL2023A03J01017)。

摘　　要：肥胖通过促进慢性系统性炎症、高胰岛素血症、循环类固醇激素升高、血糖和脂质水平升高、促进细胞因子和生长因子的产生等方式促进恶性肿瘤的发生、发展。本文通过对国内外现有文献的回顾,对肥胖相关肿瘤的发生、发展的病理生理机制及减重手术预防肥胖相关肿瘤的现状进行总结。Obesity can promote the development of tumors through accelerating chronic inflammation,hyperinsulinemia,hypercirculating steroid hormonemia,hypergycemia,hyperlipemia and the production of cytokines and growth factors.Herein,the recent literatures about the development of obesity-related tumors and the phenomenon of obesity paradox are reviewed briefly.And we summarize the current status of bariatric surgery to prevent obesity-related tumors.

关 键 词：肥胖 肿瘤 肥胖相关肿瘤 减重手术 肥胖悖论 

分 类 号：R589.2[医药卫生—内分泌] R730[医药卫生—内科学]