减重代谢手术后神经影像改变与认知功能评估的研究进展  

Progress of research in neuroimaging changes and cognitive function assessment after bariatric metabolic surgery

作　　者：刘澳 周菁 孙永兵 和俊雅 林新贝 乔琦 李中林 张建成[4] 武肖玲 邹智 胡扬喜 肖新广 吕雪[8] 李昊 李永丽[2] Liu Ao;Zhou Jing;Sun Yongbing;He Junya;Lin Xinbei;Qiao Qi;Li Zhonglin;Zhang Jiancheng;Wu Xiaoling;Zou Zhi;Hu Yangxi;Xiao Xinguang;Lv Xue;Li Hao;Li Yongli(Medical Imaging Department,People's Hospital of Zhengzhou University;Key Laboratory of Chronic Disease Health Management of Henan Province,Department of Health Management,Henan Provincial People's Hospital;Department of Medical Imaging,People's Hospital of Henan University;Department of Gastrointestinal Surgery,Henan Provincial People's Hospital;Department of Nuclear Medicine,Henan Provincial People's Hospital;Department of Metabolic Surgery,Zhengzhou Central Hospital Affiliated to Zhengzhou University;Department of Medical Imaging,Zhengzhou Central Hospital Affiliated to Zhengzhou University;Henan Provincial People's Hospital;Fuwai Central China Cardiovascular Hospital,Zhengzhou 450000,China)

机构地区：[1]郑州大学人民医院医学影像科,郑州450000 [2]河南省人民医院健康管理学科河南省慢病健康管理重点实验室 [3]河南大学人民医院医学影像科 [4]河南省人民医院胃肠外科 [5]河南省人民医院核医学科 [6]郑州大学附属郑州中心医院代谢外科 [7]郑州大学附属郑州中心医院医学影像科 [8]河南省人民医院 [9]阜外华中心血管病医院

出　　处：《中华肥胖与代谢病电子杂志》2023年第3期203-208,共6页Chinese Journal Of Obesity and Metabolic Diseases：Electronic Edition

基　　金：国家自然科学基金项目资助(82071884);河南省中青年卫生健康科技创新人才项目(YXKC2020004);河南省科技厅科技攻关项目(222102310198)。

摘　　要：肥胖是一种慢性代谢性疾病,表现为体重增长和体内脂肪的过度贮存,这种不平衡的能量代谢紊乱会造成大脑结构和功能发生改变,而与认知相关的大脑区域改变会增加发生认知障碍的风险。减重代谢手术(BMS)作为治疗肥胖和改善肥胖相关合并症的有效手段,术后脑区结构与认知功能明显改善。本文综述了BMS术后认知功能改变的神经影像学基础和认知功能评估的最新进展,讨论了BMS术后脑区结构改变对认知功能的影响,旨在为进一步探索术后认知功能改变机制研究提供参考。Obesity is a chronic metabolic disease manifested by weight gain and excessive storage of body fat.This imbalanced energy metabolism disorder causes changes in brain structure and function,while changes in brain regions associated with cognition increase the risk of cognitive impairment.Bariatric metabolic surgery(BMS)is an effective means to treat obesity and improve obesity-related complications,and the structure and cognitive function of brain regions are significantly improved after surgery.This article reviews the latest progress in the neuroimaging basis of cognitive function changes and cognitive function assessment after BMS.It discusses the impact of postoperative brain area structure changes on cognitive function,aiming to provide a reference for further exploring the mechanism of postoperative cognitive function changes.

关 键 词：减重代谢手术 神经影像学 认知功能 肥胖症 神经认知测试 

分 类 号：R656[医药卫生—外科学]