Clinical Effect of Yinhuang Qingfei Capsules in Treatment of Asymptomatic and Mild/Common Severe Acute Respiratory Syndrome Coronavirus 2 Infection:An Analysis of 242 Cases  

作　　者：Feibao CHEN Changming ZHANG Chen CHEN Ping JI Chanjuan ZHANG Yanbo LI Hao WANG Baobao GU Yanting YANG 

机构地区：[1]Hunan Anbang Pharmaceutical Co.,Ltd.,Changsha 410300,China [2]Shanghai Pudong Hospital,Shanghai 200120,China [3]Pudong New Area Pulmonary Hospital,Shanghai 200120,China [4]Nanhua Hospital of Pudong New Area,Shanghai 200120,China [5]Hunan Hengtian Medical Technology Co.,Ltd.,Changsha 410300,China [6]Shanghai Pudong Institute of Health Development,Shanghai 200120,China

出　　处：《Medicinal Plant》2024年第2期61-64,共4页药用植物：英文版

基　　金：Supported by the Science and Medicine Joint Fund Project of Natural Science Foundation of Hunan Province(2022JJ80001).

摘　　要：[Objectives]To investigate the clinical effect of Yinhuang Qingfei capsules in the treatment of asymptomatic and mild/common severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.[Methods]A total of 362 patients with SARS-CoV-2 infection were divided into the treatment group with 242 patients and control group with 120 patients according to their treatment regimen.The patients in the control group were given standard treatment regimen and those in the treatment group were given Yinhuang Qingfei capsules in addition to the treatment in the control group.The two groups were observed in terms of average length of hospital stay,mean time for nucleic acid clearance,TCM syndrome score,and progression to severe/critical illness,and clinical outcome was compared between the two groups.[Results]There was a significant difference in the overall response rate between the treatment group and the control group[97.52%(236/242)vs 95.00%(114/120),P<0.05].Compared with the control group,the treatment group had significantly shorter length of hospital stay and time for nucleic acid clearance(P<0.05).After 7 days of treatment,both groups had a significant change in TCM syndrome score,and there was a significant difference in TCM syndrome score between the two groups(P<0.05);after 15 days of treatment,both groups had a TCM syndrome score of 0.Progression to severe/critical illness was not observed in either group.[Conclusions]Compared with the standard treatment regimen alone,standard treatment regimen combined with Yinhuang Qingfei capsules can effectively shorten the length of hospital stay and time for nucleic acid clearance and improve TCM symptoms in patients with asymptomatic and mild/common SARS-CoV-2 infection.

关 键 词：Severe acute respiratory syndrome coronavirus 2 infection ASYMPTOMATIC Mild/common Yinhuang Qingfei capsules 

分 类 号：R259[医药卫生—中西医结合]