云南省傣族地区2型糖尿病视网膜病变患病率及危险因素分析  

Prevalence and Risk Factor Analysis of Type 2 Diabetic Retinopathy in the Dai Ethnic Region of Yunnan Province

作　　者：寸永康 瞿静灵 李博爱 杨眉 钟华[2] CUN Yongkang;QU Jingling;LI Boai;YANG Mei;ZHONG Hua(Department of Ophthalmology,Dehong People s Hospital,Dehong 678400,Yunnan,China;Department of Ophthalmology,The First Affiliated Hospital of Kunming Medical University,Kunming 650032,China)

机构地区：[1]德宏州人民医院眼科,云南德宏州678400 [2]昆明医科大学第一附属医院眼科,云南昆明650032

出　　处：《昆明理工大学学报（自然科学版）》2024年第2期104-111,共8页Journal of Kunming University of Science and Technology(Natural Science)

基　　金：昆医联合专项项目(202001AY070001-283)。

摘　　要：探索云南省傣族地区2型糖尿病住院患者糖尿病视网膜病变的患病率及相关危险因素.回顾分析2020年1月—2022年12月就诊于云南省德宏州人民医院眼科和内分泌科的522例T2DM患者的临床资料及彩色眼底照相结果.结合彩色眼底照相结果将入组患者分为NDR组和DR组.采用R 4.0.3统计软件进行单因素分析,比较两组的社会人口学资料、实验室检测指标和相关病史等,进一步使用二元logistic回归分析筛选DR发生可能的危险因素.522例T2DM患者中,NDR组369例,DR组153例,德宏州T2DM住院患者的DR患病率为29.31%.DR患者中傣族患者(64例,41.83%)、糖尿病病程超过5年以上者(5~10年62例、11~15年27例、16~20年38例、>20年5例)、合并高血压者(116例,75.82%)、尿素水平、eGFR降低者(35例,22.88%)均高于NDR组患者.多变量Logistic回归分析显示,傣族、病程超过5年、合并高血压三个因素可能是DR发生的危险因素,其OR值及95%CI分别为傣族2.05(1.24~3.38)、糖尿病病程5~10年3.50(1.97~6.22)、11~15年6.57(3.17~13.64)、16~20年12.95(6.04~27.77)、>20年3.56(1.05~12.01)、合并高血压1.85(1.10~3.11).云南省德宏州T2DM住院患者的DR患病率为29.31%.傣族、病程超过5年、合并高血压三个因素是DR发生的独立危险因素.This study aimed to explore the prevalence of DR and its associated risk factors among T2DM hospitalized patients in the Dai ethnic region of Yunnan Province,China.We conducted a retrospective analysis of clinical data and color fundus photography results from 522 T2DM patients admitted to the Departments of Ophthalmology and Endocrinology at the People s Hospital of Dehong Prefecture,Yunnan Province,from January 2020 to December 2022.Patients were categorized into the Non-Diabetic Retinopathy(NDR)group and the DR group based on the results of color fundus photography.The R 4.0.3 statistical software was used for single-factor analysis to compare the sociodemographic data,laboratory test indicators,and relevant medical histories between the two groups.Binary logistic regression analysis was further employed to screen for potential risk factors for the occurrence of DR.Among the 522 T2DM patients,there were 369 cases in the NDR group and 153 in the DR group,resulting in a DR prevalence rate of 29.31%among hospitalized T2DM patients in Dehong Prefecture,Yunnan Province.The number of Dai patients(64 cases,41.83%),patients with a diabetes duration of over five years(5-10 years:62 cases,11-15 years:27 cases,16-20 years:38 cases,>20 years:5 cases),patients with hypertension(116 cases,75.82%),and patients with elevated urea levels and reduced eGFR(35 cases,22.88%)in the DR group were all higher than those in the NDR group.Multivariate logistic regression analysis indicated that being Dai,having a diabetes duration of over five years,and comorbid hypertension might be independent risk factors for the development of DR,with the odds ratios(OR)and 95%confidence intervals(CI)being 2.05(1.24~3.38)for Dai ethnicity,3.50(1.97~6.22)for a diabetes duration of 5-10 years,6.57(3.17~13.64)for 11-15 years,12.95(6.04~27.77)for 16-20 years,3.56(1.05~12.01)for over 20 years,and 1.85(1.10~3.11)for comorbid hypertension.The DR prevalence rate among hospitalized T2DM patients in Dehong Prefecture,Yunnan Province,is 29.31%.Being Dai,having

关 键 词：云南省傣族地区 2型糖尿病 糖尿病视网膜病变 糖尿病视网膜病变患病率 糖尿病视网膜病变危险因素 

分 类 号：R587.2[医药卫生—内分泌] R774.1[医药卫生—内科学]