高效烯酰吗啉的制备和应用  

Preparation and application of(Z)-dimethomorph

作　　者：徐韶康 叶剑 XU Shaokang;YE Jian(Jiangsu Pesticide Research Institute Co.,Ltd.,Nanjing210046,China)

机构地区：[1]江苏省农药研究所股份有限公司,南京210046

出　　处：《现代农药》2024年第2期54-57,共4页MODERN AGROCHEMICALS

摘　　要：以邻苯二酚为起始原料,在优化的反应条件下合成了烯酰吗啉,再利用烯酰吗啉不同异构体在相同溶剂中的溶解度差异,对(Z)-异构体和(E)-异构体进行分离,得到高效烯酰吗啉((Z)-异构体),并对分离出的低效体(E)-异构体进行了消旋和循环分离。采用菌丝生长速率法测定了烯酰吗啉、高效烯酰吗啉、烯酰吗啉(E)-异构体对辣椒疫霉菌的活性。结果显示,高效烯酰吗啉对辣椒疫霉菌具有较强的抑制作用。高效烯酰吗啉具有开发应用价值。Under the optimized reaction conditions,dimethomorph was synthesized using catechol as the starting material.Based on the solubility difference of different isomers of dimethomorph in the same solvent,(Z)-isomer and(E)-isomer were separated,and(Z)-dimethomorph was obtained.(E)-isomer was racemized and cycled.The inhibitory effects of(Z)-dimethomorph on Phytophthora capsici were determined by the mycelial growth rate method.The results showed that(Z)-dimethomorph had a good antibacterial effect on Phytophthora capsici.

关 键 词：高效烯酰吗啉 烯酰吗啉 合成 活性测试 辣椒疫霉菌 

分 类 号：TQ455.47[化学工程—农药化工]