影像检查对早期检测及评估乳腺癌患者化疗后相关心功能障碍的价值  

Value of imaging techniques in early detection and assessment of cardiac dysfunction in breast cancer patients post-chemotherapy

作　　者：戚轩 王武陵 杨宏楷[1] 刘光竹 齐东 何永胜[1] QI Xuan;WANG Wuling;YANG Hongkai;LIU Guangzhu;QI Dong;HE Yongsheng(Department of Radiology,Ma'anshan People's Hospital,Ma'anshan 243000,China;Ma'anshan Clinical College,Anhui Medical University,Ma'anshan 243000,China)

机构地区：[1]马鞍山市人民医院影像科,马鞍山243000 [2]安徽医科大学马鞍山临床学院,马鞍山243000

出　　处：《磁共振成像》2024年第4期219-224,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：马鞍山市科技计划项目(编号:YL-2022-5);马鞍山市卫生健康科研项目(编号:MASWJ2022a001);皖南医学院校级科研项目(编号:JXYY2022120)。

摘　　要：乳腺癌已发展为全球第一大癌,随着诊治手段的进步,乳腺癌患者生存时间不断延长,但抗肿瘤治疗会引发心脏相关并发症,出现癌症治疗相关心功能障碍(cancer therapy related cardiac dysfunction,CTRCD)。CTRCD始于亚临床心肌细胞损伤,最终发展为有症状的心力衰竭。因此,准确评估CTRCD的发生和严重程度对于肿瘤患者的治疗和康复至关重要。随着医疗技术的不断进步,心脏影像学成为评估和管理心脏健康的关键工具,包括超声心动图、心脏计算机断层扫描(cardiac computed tomography,CCT)、心脏磁共振成像(cardiac magnetic resonance imaging,CMRI)等,在提供心脏结构和功能信息的基础上,组织特定性成像、应变成像、灌注成像等在早期识别和评估CTRCD中发挥关键作用。本文就不同影像检查技术在乳腺癌患者化疗后心功能障碍研究中的进展进行文献综述,重点论述磁共振技术在此方面的进展,以期为早期检测CTRCD提供更为精确的影像生物信息。Breast cancer has become the most prevalent cancer worldwide.With the advancement in diagnostic and therapeutic methods,the survival time of breast cancer patients has been significantly extended.However,anti-tumor treatments can lead to cardiac-related complications,resulting in cancer therapy-related cardiac dysfunction(CTRCD).CTRCD begins with subclinical myocardial cell damage and eventually develops into symptomatic heart failure.Therefore,accurately assessing the occurrence and severity of CTRCD is crucial for the treatment and recovery of cancer patients.With the continuous advancement of medical technology,cardiac imaging has become a key tool in the assessment and management of heart health.This includes echocardiography,cardiac computed tomography(CCT),and cardiac magnetic resonance imaging(CMRI).Beyond providing information on heart structure and function,techniques such as tissue-specific imaging,strain imaging,and perfusion imaging play a crucial role in the early identification and assessment of CTRCD.This article reviewed the progress of different imaging examination techniques in the study of cardiac dysfunction after chemotherapy in breast cancer patients,with a focus on the progress of MRI technology in this area,in the hope of providing more accurate imaging biological information for the early detection of CTRCD.

关 键 词：乳腺癌 化疗 心功能 心脏磁共振成像 超声心动图 心脏计算机断层扫描 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学] R541.7[医药卫生—临床医学]