HFNC气道管理对急性低氧性呼吸衰竭床旁无痛纤支镜检查患者氧合状态、血流动力学及肺顺应性的影响  

Effects of HFNC airway management on oxygenation status,hemodynamics and lung compliance in patients with acute hypoxic respiratory failure examined by bedside painless fiberoptic bronchoscopy

作　　者：冯婉贞 王岚[1] 李闪闪 Feng Wan-zhen;Wang Lan;Li Shan-shan(Department of Respiratory Medicine,The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan,China)

机构地区：[1]河南科技大学第一附属医院呼吸科,河南洛阳471000

出　　处：《四川生理科学杂志》2024年第4期715-717,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的:探讨经鼻高流量氧疗(High-flow nasal cannula,HFNC)气道管理对急性低氧性呼吸衰竭(Acute hypoxic respiratory failure,AHRF)床旁无痛纤支镜检查患者氧合状态、血流动力学及肺顺应性的影响。方法:随机将我院2021年12月至2022年12月的120例拟行床旁无痛纤支镜检查的AHRF患者分为NPPV组和HFNC组,每组60例。NPPV组予以无创正压通气(Noninvasive positive pressure ventilation,NPPV)气道管理,HFNC组予以HFNC气道管理。干预后,比较两组氧合状态、血流动力学水平及肺顺应性。结果:T2时HFNC组氧分压、氧合指数高于NPPV组,二氧化碳分压低于NPPV组(P<0.05);T1、T2时HFNC组血流动力学水平变化小于NPPV组(P<0.05);术后3 d HFNC组总顺应性、肺顺应性及胸廓顺应性水平高于NPPV组(P<0.05)。结论:HFNC气道管理应用于AHRF床旁无痛纤支镜检查患者中可有效改善患者氧合状态、血流动力学及肺顺应性。Objective:To explore the effects of airway management in high-flow nasal oxygen therapy(HFNC)on oxygenation state,hemodynamics and lung compliance of patients with Acute hypoxic respiratory failure(AHRF)examined by bedside painless fiberoptic bronchoscopy.Methods:120 patients with AHRF who planned to undergo bedside painless fiberoptic bronchoscopy from December 2021 to December 2022 were randomly divided into NPPV group and HFNC group,with 60 patients in each group.Non-invasive positive pressure ventilation(NPPV)airway management was performed in NPPV group,and HFNC airway management was performed in HFNC group.After the intervention,the oxygenation status,hemodynamic level and lung compliance were compared between the two groups.Results:At T2,the oxygen partial pressure and oxygenation indexes in HFNC group were higher than those in NPPV group,and the carbon dioxide partial pressure was lower than that in NPPV group(P<0.05).At T1 and T2,the changes of hemodynamic levels in HFNC group were smaller than those in NPPV group(P<0.05).The total compliance,lung compliance and thoracic compliance in HFNC group were higher than those in NPPV group 3 days after operation(P<0.05).Conclusion:HFNC airway management can effectively improve oxygenation status,hemodynamics,and lung compliance in patients with AHRF bedside painless bronchoscopy.

关 键 词：急性低氧性呼吸衰竭 无痛纤支镜 氧合 血流动力学 肺顺应性 

分 类 号：R563.8[医药卫生—呼吸系统]