关节镜下部分切除术联合透明质酸腔内注射对半月板损伤的治疗效果分析  

Effect analysis of arthroscopic partial resection combined with intracavitary injection of hyaluronic acid on meniscus injury

作　　者：黄素贤 Huang Su-xian(Department of Orthopaedics,The First Affiliated Hospital of Henan University of Science and Technology,Luoyang 471000,Henan,China)

机构地区：[1]河南科技大学第一附属医院骨科,河南洛阳471000

出　　处：《四川生理科学杂志》2024年第4期756-758,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的:分析关节镜下部分切除术联合透明质酸腔内注射对半月板损伤的治疗效果。方法:选取本院2021.年1月至2022年6月间收治的98例半月板损伤病人作为研究对象。随机将患者分成对照组和观察组,每组49例。对照组采用关节镜下部分切除术联合射频汽化治疗;观察组采用关节镜下部分切除术联合射频汽化治疗和透明质酸腔内注射治疗。分析对比两组的临床疗效、膝关节功能、疼痛程度以及白介素17(Interleukin;IL-17)、脂联素、IL-6水平。结果:观察组的临床疗效明显高于对照组(P<0.05)。治疗后,观察组的Lysholm评分明显高于对照组(P<0.05)。观察组术后1 m、术后3 m、术后6 m各时间点的视觉模拟评分量表(Visual analogue scale;VAS)评分均比对照组显著降低(P<0.05)。治疗后,观察组的血浆和关节腔中的IL-17、IL-6水平均显著低于对照组,脂联素水平均明显高于对照组(P<0.05)。结论:采用关节镜下部分切除术联合透明质酸腔内注射可显著提高半月板损伤患者的临床疗效,缓解疼痛,改善膝关节功能,降低炎性反应.Objective:To analyze the therapeutic effect of arthroscopic partial resection combined with intracavitary injection of hyaluronic acid on meniscus injury.Methods:98 patients with meniscus injury admitted to our hospital from January 2021 to June 2022 were selected as the study objects.The patients were randomly divided into control group and observation group,49 cases in each group.The control group was treated with arthroscopic partial resection combined with radiofrequency vaporization.The observation group was treated with arthroscopic partial resection combined with radiofrequency vaporization and intracavitary injection of hyaluronic acid.Clinical efficacy,knee function,pain degree and interleukin 17(IL17),adiponectin,IL-6 levels were analyzed and compared between the two groups.Results:The clinical effect of observation group was significantly higher than that of control group(P<0.05).After treatment,the Lysholm score of the observation group was significantly higher than that of the control group(P<0.05).Visual analogue scale(VAS)scores were significantly lower than those of control group(P<0.05).After treatment,the levels of IL-17 and IL-6 in plasma and joint cavity of observation group were significantly lower than those of control group,and the levels of adiponectin were significantly higher than those of control group(P<0.05).Conclusion:Arthroscopic partial resection combined with intraluminal injection of hyaluronic acid can significantly improve the clinical efficacy of patients with meniscal injury,relieve pain,improve knee function,and reduce inflammatory response。

关 键 词：关节镜下部分切除术 射频汽化 透明质酸腔内注射 半月板损伤 

分 类 号：R68[医药卫生—骨科学]