心电图非特异性ST段和T波异常改变与腹膜透析患者并发心血管不良事件的关系研究  

Relationship between abnormal changes of nonspecific ST segment and T wave in electrocardiogram and adverse cardiovascular events in peritoneal dialysis patients

作　　者：李俊霞 Li Jun-xia(Department of Electrocardiography,Luoyang Yiluo Hospital,Luoyang 471000,Henan,China)

机构地区：[1]洛阳伊洛医院心电图室,河南洛阳471000

出　　处：《四川生理科学杂志》2024年第4期846-848,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的:研究心电图非特异性ST段和T波异常改变与腹膜透析患者并发心血管不良事件的关系,分析其在预后的价值。方法:回顾性选择2019年2月~2021年2月于我院接受腹膜透析治疗的84例患者作为研究对象,根据患者入院时心电图非特异性ST抬高、压低、延长、缩短及T波低平、平坦、增高、倒置、双向变化,将入组患者分为ST段-T波异常组(n=40例)和ST段-T波正常组(n=44例)。收集两组性别、病史、血清指标、实验室检查水平、心血管不良事件发生率等临床资料,采用Cox比例模型分析心电图非特异性ST段和T波异常改变与腹膜透析患者并发心血管不良事件的关系。结果:两组在性别比、年龄、血脂水平、血压等方面均无统计学差异(P>0.05),但ST段-T波异常组与ST段-T波正常组在心血管不良事件发生率、透析时间、血清可溶性生长刺激基因表达蛋白2(sST2)水平上有显著差异(P<0.05);经Cox比例模型分析显示ST段-T波异常与心血管不良事件发生、透析时间、sST2水平呈正相关(P<0.05)。结论:ST段-T波异常与并发心血管不良事件发生、透析时间、sST2水平呈正相关,可作为ST段-T波异常的危险因素,根据结果加强此类患者的监管,以改善患者预后。Objective:To investigate the relationship between abnormal changes of nonspecific ST segment and T wave in electrocardiogram and adverse cardiovascular events in peritoneal dialysis patients,and to analyze their prognostic value.Methods:A total of 84 patients who received peritoneal dialysis treatment in our hospital from February 2019 to February 2021 were retrospectively selected as the study objects.According to the non-specific ECG ST elevation,depression,prolongation and shortening,and T-wave low,flat,elevated,inverted and bidirectional changes upon admission,The enrolled patients were divided into abnormal ST-segment T wave group(n=40 cases)and normal ST-segment T wave group(n=44 cases).Clinical data such as gender,medical history,serum indexes,laboratory examination level,and incidence of adverse cardiovascular events were collected in the two groups.Cox proportional model was used to analyze the relationship between abnormal changes of nonspecific ST segment and T wave in electrocardiogram and adverse cardiovascular events in peritoneal dialysis patients.Results:There were no significant differences in sex ratio,age,blood lipid level and blood pressure between the two groups(P>0.05),but there were significant differences in the incidence of cardiovascular adverse events,dialysis time and serum soluble growth stimulator gene expression protein 2(sST2)level between the abnormal ST-segment T wave group and the normal ST-segment T wave group(P<0.05).Cox proportional model analysis showed that abnormal ST-segment T wave was positively correlated with cardiovascular adverse events,dialysis time and sST2 level(P<0.05).Conclusion:Abnormal ST-segment T wave is positively correlated with the occurrence of concurrent adverse cardiovascular events,dialysis time and sST2 level,which can be used as a risk factor for abnormal ST-segment T wave.According to the results,supervision should be strengthened to improve the prognosis of patients with abnormal ST-segment T wave.

关 键 词：心电图 非特异性ST段和T波异常改变 腹膜透析 心血管不良事件 

分 类 号：R54[医药卫生—心血管疾病]