门头沟地区体检人群的甲状腺功能检测结果分析  

Analysis of thyroid function test results of medical examination population in Mentougou area

作　　者：赵金凤 岳影 李婕[1] 刘晓敏 王鹏飞[1] 崔雯[1] ZHAO Jin-feng;YUE Ying;LI Jie(Beijing Jingmei Group General Hospital,Beijing 102300,China)

机构地区：[1]北京京煤集团总医院,102300

出　　处：《中国实用医药》2024年第7期96-98,共3页China Practical Medicine

摘　　要：目的通过对本院体检人群甲状腺功能异常的分析,了解门头沟地区的甲状腺功能异常情况,为甲状腺疾病的监测和诊断提供依据。方法选取单位体检人员共398例作为研究对象,运用微粒子化学发光免疫分析技术进行促甲状腺激素(TSH)、甲状腺球蛋白抗体(TGAb)、甲状腺过氧化物酶抗体(TPOAb)检测,对其检测结果进行统计分析,比较不同年龄段体检者甲状腺功能异常检出情况,甲状腺功能正常与异常体检者的甲状腺抗体结果,不同年龄、性别体检者的甲状腺抗体结果。结果398例体检者中检出甲状腺功能异常者共22例,检出率为5.53%,其中男性9例、女性13例,女性检出率高于男性。随年龄增长甲状腺功能异常检出率增加,≥60岁女性的甲状腺功能异常检出率明显高于另外两个年龄段。甲状腺功能正常体检者的TPOAb(+)TGAb(+)检出例数为15例,检出率为3.99%;甲状腺功能异常体检者的TPOAb(+)TGAb(+)检出例数为5例,检出率为22.73%。与甲状腺功能正常体检者的3.99%相比,甲状腺功能异常体检者的TPOAb(+)TGAb(+)检出率22.73%显著更高,差异有统计学意义(P<0.05)。398例体检者中,TPOAb(+)共检出45例、阳性率为11.31%,TGAb(+)共检出39例、阳性率为9.80%。不同年龄段女性阳性检出率均明显高于男性,其中女性在20~39岁阳性检出例数最多,男性以40~59岁阳性检出例数最多。结论甲状腺功能异常以及甲状腺抗体阳性检出情况均存在性别差异,女性明显多于男性,随年龄增长检出增加,建议人群定期进行甲状腺功能的实验室检查,有助于甲状腺疾病的早发现、早治疗。Objective To understand the abnormal thyroid function in Mentougou area through the analysis of abnormal thyroid function in the medical examination population in our hospital,and to provide evidence for the monitoring and diagnosis of thyroid diseases.Methods A total of 398 medical examinees were selected as the study subjects,and thyroid stimulating hormone(TSH),thyroglobulin antibodies(TGAb)and thyroid peroxidase antibody(TPOAb)were detected by chemiluminescence microparticle immunoassay.The results were statistically analyzed to compare the detection of thyroid function abnormalities in subjects of different ages,thyroid antibody results in subjects with normal and abnormal thyroid function,and thyroid antibody results in patients of different ages and genders.Results Among the 398 subjects,there were 22 cases of abnormal thyroid function,the detection rate was 5.53%,including 9 males and 13 females,and the detection rate of females was higher than that of males.The detection rate of thyroid function abnormalities increased with age,and the detection rate of thyroid function abnormalities in women≥60 years old was significantly higher than that in the other two age groups.TPOAb(+)TGAb(+)was detected in 15 subjects with normal thyroid function,and the detection rate was 3.99%.TPOAb(+)TGAb(+)was detected in 5 subjects with abnormal thyroid function,and the detection rate was 22.73%.Compared with 3.99%in subjects with normal thyroid function,the TPOAb(+)TGAb(+)detection rate in subjects with abnormal thyroid function was significantly higher at 22.73%,and the difference was statistically significant(P<0.05).Among the 398 subjects,45 cases of TPOAb(+)were detected,with a positive rate of 11.31%,and 39 cases of TGAb(+)were detected,with a positive rate of 9.80%.The positive detection rate of women in different age groups was significantly higher than that of men,and the highest number of positive detections was found in females aged 20-39 years and in males aged 40-59 years.Conclusion There are gender difference

关 键 词：甲状腺功能异常 促甲状腺激素 甲状腺球蛋白抗体 甲状腺过氧化物酶抗体 

分 类 号：R581[医药卫生—内分泌]