口腔专科医院围手术期使用头孢西丁钠致过敏性休克1例  

Anaphylactic shock induced by cefoxitin sodium during perioperative period in oral hospital:a case report

作　　者：陈俏媚 卢勇涛 段恒 CHEN Qiao-mei;LU Yong-tao;DUAN Heng(Department of Pharmacy,Stomatological Hospital,School of Stomatology,Southern Medical University,Guangzhou 510280,China)

机构地区：[1]南方医科大学口腔医院(口腔医学院)药剂科,510280

出　　处：《中国实用医药》2024年第7期152-154,共3页China Practical Medicine

摘　　要：为临床安全使用注射用头孢西丁钠,本研究对本院口腔颌面外科1例双颌正颌患者围手术期使用注射用头孢西丁钠导致过敏性休克的发生与治疗过程进行介绍,为头孢西丁钠的临床合理用药和急症处理提供参考。本例患者发生过敏性休克后及时停药,采取吸氧、应用血管活性药物、糖皮质激素、补充血容量等一系列措施,最终抢救成功。该患者过敏性休克与注射用头孢西丁钠的关联性评价为“很可能”,使用头孢西丁钠前应当详细询问患者用药史及药物过敏史,临床药师对发生不良反应的患者要进行用药教育,避免患者今后再次重复使用该类药物。同时,加强口腔医生急救知识的培训和演练非常必要。For the safe clinical use of cefoxitin sodium for injection,this study introduces the occurrence and treatment process of anaphylactic shock caused by cefoxitin sodium for injection in 1 patient of oral and maxillofacial surgery department of our hospital during perioperative period,providing reference for rational clinical use of cefoxitin sodium and emergency management.In this case,after anaphylactic shock,a series of measures such as oxygen inhalation,vasoactive drugs,glucocorticoids and blood volume supplement has been taken,and the final rescue is successful.The evaluation of the correlation between anaphylactic shock and cefoxitin sodium for injection is"very likely".Before using cefoxitin sodium,the patient's medication history and drug allergy history should be inquired in detail.Clinical pharmacists should conduct medication education for patients with adverse reactions to avoid repeated use of such drugs in the future.At the same time,it is necessary to strengthen the training and drill of first aid knowledge of stomatologists.

关 键 词：头孢西丁钠 过敏性休克 药品不良反应 口腔医院 围手术期 

分 类 号：R969[医药卫生—药理学]