出 处:《中国医药指南》2024年第12期56-58,共3页Guide of China Medicine
摘 要:目的探讨多磺酸粘多糖乳膏联合京万红软膏在治疗Ⅰ、Ⅱ期压疮的效果。方法选择2022年4月至2023年9月在本院骨科收治的带入Ⅰ、Ⅱ期压疮患者60例参与研究,按照随机数字表法分为试验组与对照组,每组30例,对照组使用传统换药治疗,试验组采用多磺酸粘多糖乳膏联合京万红软膏治疗。对比两组治疗后的临床疗效、临床指标、治疗舒适度、治疗前后创面恢复及生活质量的差异性。结果对照组治疗有效率为63.33%(19/30),试验组的治疗有效率为86.67%(26/30),试验组的治疗有效率高于对照组,差异具有统计意义(P<0.05);试验组在水泡吸收时间、创面结痂时间、压疮愈合时间、换药次数均低于对照组,差异具有统计意义(P<0.05);对照组治疗舒适度为66.67%(20/30),试验组的治疗舒适度为90.00%(27/30),试验组的治疗舒适度高于对照组(P<0.05);两组在治疗前,PUSH评分和WHOQOL—Bref评分差异无统计学意义(P>0.05);治疗后,两组PUSH评分均比治疗前有所降低,WHOQOL—Bref评分有所升高,且试验组PUSH评分低于对照组,WHOQOL—Bref评分高于对照组(P<0.05)。结论多磺酸粘多糖乳膏联合京万红软膏治疗Ⅰ、Ⅱ期压疮中发挥良好的功效,能提高临床的治疗效果,促进伤口愈合,提高患者治疗的舒适感和生活质量。Objective To investigate the effect of mucopolysaccharide polysulfonate cream combined with Jingwanhong ointment in the treatment of stageⅠandⅡpressure ulcers.Methods A total of 60 patients with stageⅠandⅡpressure ulcers admitted to the department of orthopedics of our hospital from April 2022 to September 2023 were selected,and the above patients were divided into two groups,experimental group and control group,with the same number of patients in each group as 30 cases.Among them,the patients in the control group were treated with the traditional dressing change method and,while the patients in the experimental group chose to use the treatment regimen of mucopolysaccharide cream sulfonate and Jingwanhong ointment.The clinical efficacy,clinical indexes,treatment comfort,wound recovery and quality of life were compared between the two groups after treatment.Results The control group exhibited a treatment effectiveness of 63.33%(19/30),whereas the experimental group demonstrated a higher treatment effectiveness of 86.67%(26/30).The therapeutic outcomes in the experimental group were significantly better than those in the control group,with a statistically significant difference(P<0.05).Additionally,the experimental group showed statistically significant differences(P<0.05)in blister absorption time,wound scabbing time,pressure sore healing time,and the number of dressing changes,all of which were lower compared to the control group.In terms of treatment comfort,the control group reported a rate of 66.67%(20/30),while the experimental group reported a higher treatment comfort rate of 90.00%(27/30).The treatment comfort level in the experimental group was superior to that in the control group(P<0.05).There were no statistically significant differences(P>0.05)between the control and experimental groups in PUSH scores and WHOQOL—Bref scores before treatment.However,post-treatment,both groups demonstrated a decrease in PUSH scores and an increase in WHOQOL—Bref scores.The experimental group exhibited lower P
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