Aerosol jet printing of surface acoustic wave microfluidic devices  

作　　者：Joseph Rich Brian Cole Teng Li Brandon Lu Hanyu Fu Brittany N.Smith Jianping Xia Shujie Yang Ruoyu Zhong James L.Doherty Kanji Kaneko Hiroaki Suzuki Zhenhua Tian Aaron D.Franklin Tony Jun Huang 

机构地区：[1]Department of Biomedical Engineering,Duke University,Durham,NC 27708,USA [2]Department of Electrical and Computer Engineering,Duke University,Durham,NC 27708,USA [3]Department of Mechanical Engineering,Virginia Polytechnic Institute and State University,Blacksburg,VA 24061,USA [4]Thomas Lord Department of Mechanical Engineering and Materials Science,Duke University,Durham,NC 27708,USA [5]Deptartment of Precision Mechanics,Faculty of Science and Engineering,Chuo University,Tokyo 112-8551,Japan [6]Department of Chemistry,Duke University,Durham,NC 27708,USA

出　　处：《Microsystems & Nanoengineering》2024年第1期231-242,共12页微系统与纳米工程（英文）

基　　金：support from the National Science Foundation(CMMI-2104526,CMMI-2243771,and CMMI-2104295);the Department of Energy(DE-NE0009187);the National Institutes of Health(R01GM132603,R01GM144417,and R01GM135486);supported by the National Science Foundation Graduate Research Fellowship under Grant No.2139754 for J.R.and B.S.

摘　　要：The addition of surface acoustic wave(SAW)technologies to microfluidics has greatly advanced lab-on-a-chip applications due to their unique and powerful attributes,including high-precision manipulation,versatility,integrability,biocompatibility,contactless nature,and rapid actuation.However,the development of SAW microfluidic devices is limited by complex and time-consuming micro/nanofabrication techniques and access to cleanroom facilities for multistep photolithography and vacuum-based processing.To simplify the fabrication of SAW microfluidic devices with customizable dimensions and functions,we utilized the additive manufacturing technique of aerosol jet printing.We successfully fabricated customized SAW microfluidic devices of varying materials,including silver nanowires,graphene,and poly(3,4-ethylenedioxythiophene)polystyrene sulfonate(PEDOT:PSS).To characterize and compare the acoustic actuation performance of these aerosol jet printed SAW microfluidic devices with their cleanroom-fabricated counterparts,the wave displacements and resonant frequencies of the different fabricated devices were directly measured through scanning laser Doppler vibrometry.Finally,to exhibit the capability of the aerosol jet printed devices for lab-on-a-chip applications,we successfully conducted acoustic streaming and particle concentration experiments.Overall,we demonstrated a novel solution-based,direct-write,single-step,cleanroom-free additive manufacturing technique to rapidly develop SAW microfluidic devices that shows viability for applications in the fields of biology,chemistry,engineering,and medicine.

关 键 词：PRINTING WAVE FLUID 

分 类 号：TP334.8[自动化与计算机技术—计算机系统结构]