槟榔化学成分和检验技术研究进展  

Research Progress on the Detection Technology and Chemical Constituents of Areca Catechu

作　　者：陈学国 杜瑞轩[2] 魏京莲 王丹 Chen Xue-guo;Du Rui-xuan;Wei Jing-ian;Wang Dan(Key Laboratory of Forensic Toxicology,Ministry of Public Security,Beijing 100192,China;Criminal Investigation Police University of China,Shenyang,Liaoning 110035,China;Qingdao West Coast New Area Market Supervision Administration,Qingdao,Shandong 266555,China)

机构地区：[1]法庭毒物分析公安部重点实验室,北京100192 [2]中国刑事警察学院,辽宁沈阳110035 [3]青岛西海岸新区市场监督管理局,山东青岛266555

出　　处：《福建分析测试》2024年第2期16-20,27,共6页Fujian Analysis & Testing

基　　金：法庭毒物分析公安部重点实验室开放课题(No.2023FTDWFX03);2023年度中国刑事警察学院中央高校基本科研业务费项目(No.C2023009);2023年度教育厅基本科研项目(No.JYTMS20231413)。

摘　　要：作为一种药材,槟榔的药用历史悠久,在我国多地区存在嚼食槟榔的习惯。但是,长时间的大量嚼食槟榔不仅能导致口腔黏膜纤维化、口腔癌等多种疾病,而且会引起中毒,我国多地已经颁布禁售槟榔的规定,部分国家将其列为毒品进行管制。槟榔的化学成分复杂,生物碱成分是其主要的活性成分。本文在统计国内外关于槟榔的研究数据基础上,概述了槟榔主要化学成分的理化性质、毒性和毒理作用,介绍了槟榔中主要化学成分的提取技术与检测方法研究现状,旨在为槟榔及其制品的市场监督与管控提供技术支持,为槟榔滥用案件物证鉴定提供科学依据。Areca catechu has a long history of medication,and peoples in many places of China also have the habit of chew‐ing it.However,chewing areca catechu in large quantities for a long time will lead to oral mucosal fibrosis,oral cancer and other diseases.Relevant regulations have issued to ban the sale of areca catechu in many places.Based on the summary of physical and chemical properties,toxicity and toxicology of the main constituents of areca catechu,the research progress of samples treatments and detection technology of chemical constituents in areca catechu in this paper were discussed in de‐tails aiming to provide technical support for the supervision and control of areca catechu and corresponded products market,and provide scientific and theoretical basis for the trace evidences identification of relevant cases.

关 键 词：槟榔 化学成分 检验技术 进展 

分 类 号：R284[医药卫生—中药学]