绝经后女性中轴骨与外周骨骨密度的测量分析  

Measurement and analysis of DXA of mid-axial and peripheral bone in postmenopausal women

作　　者：李楠 辛力 李胜利 袁峰 LI Nan;XIN Li;LI Shengli;YUAN Feng(Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221006,China)

机构地区：[1]徐州医科大学附属医院,江苏徐州221006

出　　处：《中国骨质疏松杂志》2024年第4期500-503,537,共5页Chinese Journal of Osteoporosis

基　　金：江苏省卫生健康委科研项目(ZD2022064)。

摘　　要：目的比较双能X线吸收检测仪(dual-energy X-ray absorptiometry,DXA)检测中轴骨密度和外周骨密度的骨质疏松诊断结果,并研究DXA测量不同部位的骨密度及其随年龄变化的关系。方法收集2020年12月至2022年2月在徐州医科大学附属医院骨质疏松科就诊的518例患者资料,年龄50~89岁,平均(67.8±8.8)岁。依据年龄分为4组,用DXA测量受试者中轴骨密度T值及外周骨密度T值,比较两者在诊断骨质疏松时的差异,并行一致性检验。记录各组腰1-4、全髋、股骨颈DXA T值,并观察各部位骨密度随年龄变化的特点。结果中轴DXA和外周DXA诊断骨质疏松时差异有统计学意义(χ^(2)=188.65,P<0.05),两种检查方法的一致性较弱(Kappa=0.2,P<0.05)。中轴骨密度各部位T值存在差异,且随年龄变化趋势不同。结论中轴骨密度结合外周骨密度可以提高骨质疏松的检出率,中轴骨不同部位间骨密度T值不能相互替代。Objective To compare the result of dual-energy X-ray absorptiometry(DXA)for the diagnosis of osteoporosis by the detection of mid-axial and peripheral bone density,and to study the relationship between DXA measurements of bone density at different sites and its changes with age.Methods 518 patients aged 50-89 with an average age of(67.8±8.8)years were collected from the Osteoporosis Department of the Affiliated Hospital of Xuzhou Medical University from December 2020 to February 2022.Divided the subjects into 4 groups based on age,measured the T-scores of axial bone density and peripheral bone density using DXA,compared the differences between the two in diagnosing osteoporosis,and conducted consistency tests.Recorded the DXA T-scores of Lumbar 1-4,total hip,and femoral neck in each group,and observed the characteristics of bone density changes in each area with age.Results The difference between mid-axial DXA and peripheral DXA in the diagnosis of osteoporosis was statistically significant(χ^(2)=188.65,P<0.05),and the concordance between the two tests was statistically significant,with a weak concordance(Kappa=0.2,P<0.05).There were differences in T-scores between sites of mid-axial BMD and different trends with age.Conclusion The combination of mid-axial BMD with peripheral BMD can improve the detection rate of osteoporosis,and BMD T-scores between different parts of the mid-axial bone cannot be substituted for each other.

关 键 词：骨质疏松 骨密度 双能X线吸收检测仪 T值 

分 类 号：R681[医药卫生—骨科学]