围产期孕妇生殖道B族链球菌感染对妊娠结局的影响及危险因素  

Effect of perinatal reproductive tract group B streptococcus infection on pregnancy outcome and risk factors

作　　者：陈静 孙昌历 袁燕 张琳媛 刘茂永 CHEN Jing;SUN Chang-li;YUAN Yan;ZHANG Lin-yuan;LIU Mao-yong(The Third Affiliated Hospital of Zunyi Medical University(The First People's Hospital of ZunyiCity),Zunyi,Guizhou 563000,China)

机构地区：[1]遵义医科大学第三附属医院(遵义市第一人民医院)产科,贵州遵义563000

出　　处：《中华医院感染学杂志》2024年第7期1091-1094,共4页Chinese Journal of Nosocomiology

基　　金：贵州科研基金资助项目(2021KJ024401)。

摘　　要：目的分析生殖道B族链球菌(GBS)感染对围产期孕妇妊娠结局的影响及其易感因素,为GBS感染的防治提供参考。方法选择遵义市第一人民医院2020年1月-2022年3月收治的615例围产期孕妇分为感染组(92例)和非感染组(523例),分组依据为围产期是否发生生殖道GBS感染。统计两组妊娠结局,分析围产期孕妇生殖道GBS感染的易感因素。结果感染组宫内窘迫、新生儿窒息、低出生体质量儿、早产发生率更高(P<0.05);有妊娠糖尿病、年龄≥35岁、有阴道炎、有流产史、Nugent评分≥4分、阴道清洁度Ⅲ~Ⅳ度、酸碱度(pH)值≥5.0均为围产期孕妇生殖道GBS感染的易感因素(P<0.05);孕前检查是围产期孕妇生殖道GBS感染的保护因素(P<0.05)。结论生殖道GBS感染可增加围产期孕妇不良妊娠结局发生的风险,其影响因素较多,临床可据此对有以上特征的孕妇进行针对性治疗或干预,降低其围产期生殖道GBS感染的风险,改善其妊娠结局。OBJECTIVE To analyze the influence of reproductive tract group B streptococcus(GBS)infection on perinatal pregnancy outcome and its predisposition factors,in order to provide reference for prevention and treat-ment of GBS infection.METHODS A total of 615 perinatal pregnant women admitted to the First People's Hospi-tal of Zunyi City from Jan 2020 to Mar 2022 were enrolled and divided into the infected group(92 cases)and non-infected group(523 cases),according to whether reproductive tract GBS infection occurred in the perinatal peri-od.The pregnancy outcomes between the two groups were analyzed,and the predisposing factors of reproductive tract GBS infection in perinatal women were analyzed.RESULTS The incidence of intrauterine distress,neonatal asphyxia,low birth weight and preterm delivery were higher in the infection group(P<0.05).Gestational diabe-tes mellitus,age≥35 years,vaginitis,history of abortion,Nugent score≥4,vaginal cleanliness m-Ⅳ,pH≥5.0 were all risk factors for reproductive tract GBS infection in perinatal women(P<0.05).Prepregnancy exami-nation was a protective factor for reproductive GBS infection in perinatal women(P<0.05).CONCLUSION Re-productive GBS infection can increase the risk of adverse pregnancy outcomes in perinatal pregnant women,and there are many influencing factors.Therefore,targeted treatment or intervention can be carried out for pregnant women with the above characteristics to reduce the risk of perinatal reproductive GBS infection and improve the pregnancy outcome.

关 键 词：孕妇 围产期 生殖道 B族链球菌 妊娠结局 危险因素 

分 类 号：R714.7[医药卫生—妇产科学]