What is the effect of Tribulus terrestris on testicular morphology and sperm production?An experimental study in the rat model  

作　　者：Marcello Henrique Araujo Da Silva Gabriela Faria Buys-Goncalves Joao Henrique Duque Reis Estrada Francisco Jose Barcellos Sampaio Diogo Benchimol de Souza 

机构地区：[1]Urogenital Research Unit,Rio de Janeiro State University,Rio de Janeiro 20551-030,RJ,Brazil

出　　处：《Asian Journal of Andrology》2024年第1期67-70,共4页亚洲男性学杂志（英文版）

基　　金：This study was supported by grants from the Foundation for Research Support of Rio de Janeiro(FAPERJ,grant No.E26/201.098/2022);the Coordination of Improvement of Higher Education Personnel(CAPES);the National Council for Scientific and Technological Development(CNPq,grant No.302808/2022-1).

摘　　要：The objective of this study was to investigate whether treatment with Tribulus terrestris(Tt)has any impact on the testicular morphology and function in a rodent model.Twenty male rats were divided into a control group and a group receiving 100 mg kg^(-1) body weight of Tt supplementation.After 4o days of experiment,the animals were submitted to euthanasia;epididymal tail spermatozoa were collected;and spermatozoa concentration,motility,and viability were analyzed.In addition,testicles were collected and processed for histomorphometrical analyses.Data were compared using the Student's t-test and considered significant when P<O.05.Spermatozoa concentration,motility,and viability showed no difference between the groups.Further,testicular weight and volume,seminiferous tubule diameter,tunica propria surface density,seminiferous epithelium surface density,and intertubular compartment surface density were statistically similar between the groups.However,seminiferous epithelium height and tubular lumen surface density were augmented in animals treated with Tt.Treatment with Tt does not cause a major impact on testicular morphology,promoting only subtle modifications.No difference on spermatozoa parameters was observed.

关 键 词：MORPHOMETRY TESTICLE Tribulus terrestris 

分 类 号：R698.2[医药卫生—泌尿科学]