The Magnaporthe oryzae effector Avr-PikD suppresses rice immunity by inhibiting an LSD1-like transcriptional activator  

作　　者：Jiayuan Guo Yiling Wu Jianqiang Huang Kaihui Yu Meilian Chen Yijuan Han Zhenhui Zhong Guodong Lu Yonghe Hong Zonghua Wang Xiaofeng Chen 

机构地区：[1]Fujian Universities Engineering Research Center of Marine Biology and Drugs,Fuzhou Institute of Oceanography,College of Geography and Oceanography,Minjiang University,Fuzhou 350108,Fujian,China [2]Rice Research Institute,Fujian Academy of Agricultural Sciences,Fuzhou 350018,Fujian,China [3]Ministerial and Provincial Joint Innovation Center for Safety Production of Cross-Strait Crops,Minjiang University,Fuzhou 350108,Fujian,China [4]State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops,College of Plant Protection,Fujian Agriculture and Forestry University,Fuzhou 350002,Fujian,China

出　　处：《The Crop Journal》2024年第2期482-492,共11页作物学报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(31401692,31901960,32272513,32001976);the Natural Science Foundation of Fujian Province(2019J01766,2023J011418,2020J05177);Fujian Provincial Science and Technology Key Project(2022NZ030014);External Cooperation Program of Fujian Academy of Agricultural Sciences(DWHZ-2024-23);State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crop Opening Project(SKL2019005);Project of Fujian Provincial Department of Education(JAT190627)。

摘　　要：Avirulence effectors(Avrs),encoded by plant pathogens,can be recognized by plants harboring the corresponding resistance proteins,thereby initiating effector-triggered immunity(ETI).In susceptible plants,however,Avrs can function as effectors,facilitating infection via effector-triggered susceptibility(ETS).Mechanisms of Avr-mediated ETS remain largely unexplored.Here we report that the Magnaporthe oryzae effector Avr-PikD enters rice cells via the canonical cytoplasmic secretion pathway and suppresses rice basal defense.Avr-PikD interacts with an LSD1-like transcriptional activator AKIP30 of rice,and AKIP30 is also a positive regulator of rice immunity,whereas Avr-PikD impedes its nuclear localization and suppresses its transcriptional activity.In summary,M.oryzae delivers Avr-PikD into rice cells to facilitate ETS by inhibiting AKIP30-mediated transcriptional regulation of immune response against M.oryzae.

关 键 词：Magnaporthe oryzae Avirulence effector Avr-PikD Effector-triggered susceptibility Rice immunity Transcriptional activator 

分 类 号：S435.111.41[农业科学—农业昆虫与害虫防治]