新型冠状病毒感染对阻塞性睡眠呼吸暂停综合征患者无痛胃镜检查中呼吸功能的影响  

Effect of Corona Virus Disease 2019 Infection on Respiratory Function During Painless Gastrointestinal Endoscopy in Patients with Obstructive Sleep Apnea Syndrome

作　　者：付琦[1] 廉仲明 秦菲菲 黄亚茹 田丹丹[1] FU Qi;LIAN Zhongming;QIN Feifei;HUANG Yaru;TIAN Dandan(Department of Anesthesiology,Pain and Perioperative Medicine,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院麻醉与围术期医学部,河南郑州450052

出　　处：《河南医学研究》2024年第8期1411-1414,共4页Henan Medical Research

摘　　要：目的调查新型冠状病毒(COVID-19)感染对于阻塞性睡眠呼吸暂停综合征(OSAS)患者接受无痛胃镜检查时呼吸功能的影响。方法选取2023年1—3月于郑州大学第一附属医院接受无痛胃镜检查且合并OSAS的60例患者,根据是否感染过COVID-19分为两组,对照组(未感染组)30例,观察组(已感染组)30例。监测患者血氧饱和度(SpO 2)、心电图、血压。比较两组呼吸抑制情况、生命体征、不良反应发生率以及患者满意度。结果观察组呼吸暂停次数多于对照组,呼吸暂停总时间长于对照组(P<0.05);两组呼吸暂停发生率差异无统计学意义(P>0.05)。两组心率、SpO 2及平均动脉压组内及组间各时间点比较,差异无统计学意义(P>0.05)。观察组心动过缓发生率高于对照组(P<0.05);两组低血压、恶心呕吐发生率及患者满意度差异均无统计学意义(P>0.05)。结论COVID-19感染可使接受无痛胃镜检查时OSAS患者的呼吸暂停次数增加,呼吸暂停总时间延长,患者呼吸抑制风险显著提高。Objective To investigate the effect of corona virus disease 2019(COVID-19)infection on respiratory function during painless gastrointestinal endoscopy in patients with obstructive sleep apnea syndrome(OSAS).Methods Sixty patients who underwent gastroscopy combined with OSAS at the First Affiliated Hospital of Zhengzhou University from January to March 2023 were selected and divided into two groups according to whether been infected with COVID-19,30 patients in the control group(uninfected group)and 30 patients in the observation group(infected group).The patients’percutaneous arterial oxygen saturation(SpO 2),electrocardiogram and blood pressure were monitored.The respiratory depression,fluctuation of vital signs,incidence of adverse reactions and patient satisfaction were compared between the two groups.Results The number of apneas in the observation group was more than the control group,and the total duration of apneas was longer than that in the control group(P<0.05).There was no statistically difference in the incidence of apnea between the two groups(P>0.05).There was no statistically difference in heart rate,SpO 2 and mean artery pressure between the two groups and different time points(P>0.05).The incidence of bradycardia in the observation group was higher than that in the control group(P<0.05).There was no statistically difference in the incidence of hypotension and nausea and vomiting and patient satisfaction between the two groups(P>0.05).Conclusion COVID-19 infection can increase the number of apneas,prolong the total duration of apnea,and increase the risk of respiratory depression in patients with OSAS undergoing painless gastrointestinal endoscopy.

关 键 词：新型冠状病毒 阻塞性睡眠呼吸暂停综合征 无痛胃镜检查 呼吸抑制 不良反应 

分 类 号：R183.3[医药卫生—流行病学]