三维超声血管斑块定量参数NWI、GSM对颈动脉斑块性质的评估价值  

Evaluate Value of Three-Dimensional Ultrasound Quantitative Parameters NWI and GSM in Qualitative of Carotid Plaques

作　　者：郭文博 史景璐 张嵘 GUO Wenbo;SHI Jinglu;ZHANG Rong(Ultrasound Medicine Department,the Fifth Clinical Medical College of Henan University of Chinese Medicine(Zhengzhou People’s Hospital),Zhengzhou 450000,China;Gynaecology and Obstetrics Department,Zhengzhou Seventh People’s Hospital,Zhengzhou 450000,China)

机构地区：[1]河南中医药大学第五临床医学院(郑州人民医院)超声医学科,河南郑州450000 [2]郑州市第七人民医院妇产科,河南郑州450000

出　　处：《河南医学研究》2024年第8期1423-1426,共4页Henan Medical Research

摘　　要：目的分析三维超声血管斑块定量参数标准化管壁指数(NWI)、灰阶中位数(GSM)对颈动脉斑块性质的评估价值。方法回顾性收集2019年6月至2022年11月108例于郑州人民医院接受颈动脉斑块超声检查的患者病历资料。根据病理检查结果分为稳定斑块组(51例)与易损斑块组(64例)。两组均接受三维超声血管斑块定量检测及颈动脉内膜剥脱术。比较发生易损斑块的影响因素,并分析三维超声血管斑块定量参数NWI、GSM对颈动脉斑块性质的评估价值。结果易损斑块体积、厚度、最大面积狭窄率及GSM低于稳定板块,NWI高于稳定斑块(P<0.05);经logistic回归分析显示,三维超声血管斑块定量参数NWI、GSM均为易损斑块的重要影响因素(P<0.05);经受试者工作特征曲线分析,三维超声血管斑块定量参数NWI评估颈动脉易损斑块的曲线下面积、特异度高于GSM,GSM评估颈动脉易损斑块的灵敏度高于NWI(P<0.05)。结论对颈动脉斑块患者采用三维超声血管斑块定量参数NWI、GSM检测,可帮助对斑块回声进行量化分析,同时也有利于对斑块累及血管负荷进行评估,对患者血管斑块具有较高的定性评估价值。Objective To analyze the evaluate value of three-dimensional ultrasound quantitative parameters normalized wall index(NWI)and gray scale median(GSM)in qualitative of carotid plaques.Methods The medical records of 108 patients who underwent carotid plaque ultrasound examination in Zhengzhou People’s Hospital from June 2019 to November 2022 were collected retrospectively.According to the pathological examination results,they were divided into stable plaque group(51 cases)and vulnerable plaque group(64 cases).All patients underwent three-dimensional ultrasound quantitative detection of plaques and carotid endarterectomy.The influencing factors of vulnerable plaque were compared.The value of three-dimensional ultrasound quantitative parameters NWI and GSM in evaluating the nature of carotid plaques was analyzed.Results The volume,thickness,maximum stenosis rate and GSM of vulnerable plaques were lower than those of stable plaques,and NWI was higher than stable plaques(P<0.05).Logistic regression analysis showed that the quantitative parameters NWI and GSM of three-dimensional ultrasound vascular plaques were important influencing factors for vulnerable plaques(P<0.05).Receiver operating characteristic curve analysis found that the area under the curve and specificity of NWI for evaluating vulnerable carotid plaques were higher than those of GSM,and the sensitivity of GSM for evaluating vulnerable carotid plaques was higher than that of NWI(P<0.05).Conclusion Three-dimensional ultrasound vquantitative parameters NWI and GSM are helpful for qualitative analysis of plaques and assessment of vascular load involved in plaques.

关 键 词：颈动脉斑块 三维超声 标准化管壁指数 灰阶中位数 

分 类 号：R445.1[医药卫生—影像医学与核医学]