慢性阻塞性肺疾病患者吸入剂合理用药科普的干预效果及评价  

Intervention effect and evaluation of rational drug use popularization of inhalants in patients with chronic obstructive pulmonary disease

作　　者：罗载荣 黎燕妹 李成志 梁桥兰 LUO Zai-rong;LI Yan-mei;LI Cheng-zhi(Pharmacy Department of Tongjiang Hospital,Foshan 528300,China.)

机构地区：[1]广东同江医院药剂科,广东佛山528300

出　　处：《中国处方药》2024年第4期49-52,共4页Journal of China Prescription Drug

基　　金：佛山市卫生健康局医学科研课题(20230346)。

摘　　要：目的观察慢性阻塞性肺疾病患者吸入剂合理用药科普的干预效果。方法纳入某院2022年6月~2023年6月收治慢性阻塞性肺疾病患者100例,使用数字随机法将所有患者分为观察组及对照组两组,每组50例。观察组由呼吸科医师制订规范治疗方案,在试验过程中,由临床药师负责患者的药物监测;对照组由呼吸科医师制订规范治疗方案,并建立档案收集记录。观察两组患者肺功能情况、呼吸困难症状及生活质量改善情况、疾病管理相关依从性和药物不良反应发生情况。结果观察组患者的肺功能情况显著好于对照组患者,差异有统计学意义(P<0.05);观察组患者的呼吸困难症状和生活质量改善情况比对照组更好,差异有统计学意义(P<0.05);观察组患者的疾病管理相关依从性比对照组更高,差异有统计学意义(P<0.05);观察组患者的药物不良反应发生情况比对照组更少,差异有统计学意义(P<0.05)。结论合理用药科普干预可改善患者戒烟情况、吸入剂正确使用情况、慢性阻塞性肺疾病防治知识知晓率、肺功能情况和症状。还可以减少急性加重发作,同时也避免了药物的不良反应的增加,该方法能有效地提高患者的生存质量。Objective To observe the intervention effect of rational drug use popularization of inhalants in patients with chronic obstructive pulmo�nary disease.Methods A total of 100 patients with chronic obstructive pulmonary disease were included in a hospital from June 2022 to June 2023.All patients were divided into observation group and control group by digital random method,with 50 cases in each group.In observation group,a respiratory physician formulated a standard treatment plan,and clinical pharmacists were responsible for drug monitoring of patients during the experiment.In the control group,the standard treatment plan was formulated by respiratory physicians,and records of archive collection are established.Pulmonary function,dyspnea symptoms,improvement of quality of life,compliance with disease management and adverse drug reactions were observed in the two groups.Results The lung function of observation group was significantly better than that of control group,the difference was statistically significant(P<0.05).The dyspnea symptoms and quality of life in observation group were improved better than those in control group,and the difference was statistically significant(P<0.05).The disease management compliance of patients in observation group was higher than that in control group,the difference was statistically significant(P<0.05).The occurrence of adverse drug reactions in observation group was less than that in control group,and the difference was statistically significant(P<0.05).Conclusion Rational drug use popularization can improve patients'smoking cessation,correct use of inhalants,awareness rate of prevention and treatment knowledge of chronic obstructive pulmonary disease,lung function and symptoms.And it can reduce acute exacerbation and avoid the increase of adverse drug reactions.This method can effectively improve the quality patients life.

关 键 词：慢性阻塞性肺疾病 吸入剂 合理用药科普 干预效果 

分 类 号：R563.9[医药卫生—呼吸系统] R969[医药卫生—内科学]