美罗培南再激发致严重血小板减少一例并文献复习  

Meropenem rechallenge induced severe thrombocytopenia:a case report and review of literature

作　　者：巩学峰 苏长海[3] 田宜玄 张晴 李焕婷 GONG Xue-feng;SU Chang-hai;TIAN Yi-xuan(Baotou Medical College,Baotou 014040,China;Department of Pharmacy,the People's Hospital of DaLaTe,Ordos 014300,China.;不详)

机构地区：[1]包头医学院,内蒙古包头014040 [2]达拉特旗人民医院药剂科,内蒙古鄂尔多斯014300 [3]鄂尔多斯市中心医院药剂科,内蒙古鄂尔多斯017000

出　　处：《中国处方药》2024年第4期82-86,共5页Journal of China Prescription Drug

摘　　要：目的探讨美罗培南致血小板减少患者的临床特点,为临床安全用药提供参考。方法分析1例美罗培南抗感染治疗过程中引起血小板减少的病例,检索相关文献探讨美罗培南引起血小板减少的临床特点。结果美罗培南可致患者血小板减少,使患者住院时间延长。结论高龄、肾功能不全、联用其他抗菌药物或抗血栓形成药的患者使用美罗培南治疗过程中需主动监测相关药品不良反应。Objective To explore the clinical characteristics and case analysis of meropenem induced thrombocytopenia,to provide reference for safe clinical use.Methods A case of thrombocytopenia induced by meropenem was analyzed in the course of anti-infective treatment and the clinical characteristics of meropenem induced thrombocytopenia was discussed based on relevant literature.Results Meropenem can cause thrombocytopenia and prolonged hospital stay.Conclusion Meropenem treatment should be actively monitored for adverse drug reactions in elderly and patients with renal insufficiency and combination with other antibiotics or antithrombotics.

关 键 词：美罗培南 血小板减少 全血细胞减少 药品不良反应 

分 类 号：R978[医药卫生—药品]