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作 者:侯冯彬 黄少莹 邱世明 贺昀 梁粤 HOU Fengbin;HUANG Shaoying;QIU Shiming;HE Yun;LIANG Yue(Department of Traditional Therapy,Qiaoli Hospital of Traditional Chinese Medicine,Guangdong Province,Zhuhai 519100,China;Department of Acupuncture and Rehabilitation,Qiaoli Hospital of Traditional Chinese Medicine,Guangdong Province,Zhuhai 519100,China)
机构地区:[1]珠海市斗门区侨立中医院传统疗法科,广东珠海519100 [2]珠海市斗门区侨立中医院针灸康复科,广东珠海519100
出 处:《中国中医药现代远程教育》2024年第11期95-98,共4页Chinese Medicine Modern Distance Education of China
基 金:广东省中医药局科研项目【No.20202177】;广东省珠海市医学科研基金项目【No.ZH3310200057PJL】。
摘 要:目的观察细银质针治疗不同中医证型围绝经期膝骨性关节炎患者的效果,及其对炎性因子和雌二醇(E2)表达水平的影响。方法选取2018年1月—2022年4月广东省珠海市斗门区侨立中医院收治的153例围绝经期女性膝骨性关节炎患者为研究对象,根据所用针法的不同分为细银质针组和温针组。比较两组治疗前后视觉模拟量表(VAS)、西安大略和麦克马斯特大学骨性关节炎指数(WOMAC)评分及炎症因子、E2水平。结果细银质针组总有效率为82.79%(101/122),显著高于温针组的61.29%(19/31)(P<0.05);且细银质针组总有效率寒湿阻滞型为90.91%(30/33)、肝肾亏虚型为86.67%(26/30),明显高于瘀血阻滞型的67.86%(19/28)、湿热阻滞型的64.52%(20/31)(P<0.05)。治疗后,两组患者VAS、WOMAC评分和炎症因子、E2水平均优于治疗前,且细银质针组优于温针组(P<0.05)。结论细银质针治疗围绝经期膝骨性关节炎效果显著,且对寒湿阻滞型、肝肾亏虚型的效果优于湿热阻滞型、瘀血阻滞型,且能改善患者炎症因子和E2水平,值得临床推广应用。Objective To observe the curative effect of fine silver needle on knee osteoarthritis in perimenopausal women with differ⁃ent TCM syndromes,and its effect on inflammatory factors and estradiol(E2)expression levels.Methods A total of 153 perimeno⁃pausal female patients with knee osteoarthritis admitted to Qiaoli Hospital of Traditional Chinese Medicine from January 2018 to April 2022 were selected and divided into fine silver acupuncture group and warm acupuncture group according to different acupuncture methods.VAS,WOMAC scores,inflammatory cytokines and E2 levels were compared between the two groups before and after treat⁃ment.Results The total effective rate of fine silver acupuncture group was 82.79%(101/122),which was significantly higher than that of warm acupuncture group(61.29%,19/31)(P<0.05).The total effective rate of cold-dampness block type was 90.91%(30/33)and liver and kidney deficiency type was 86.67%(26/30),which was significantly higher than that of blood stasis block type 67.86%(19/28)and dampness-heat block type(64.52%,20/31)(P<0.05).After treatment,VAS,WOMAC scores,inflammatory factors and E2 levels in 2 groups were better than before treatment,and the fine silver acupuncture group was better than the warm acupuncture group(P<0.05).Conclusion Fine silver needle has significant curative effect in the treatment of perimenopausal female knee osteoarthritis,and the curative effect of cold-dampness block type and liver-kidney deficiency type is better than that of dampness-heat block type and blood stasis block type,which can improve the level of inflammatory factors and E2 level,and is worthy of clinical application.
关 键 词:痹证 膝骨性关节炎 细银质针疗法 寒湿阻滞证 肝肾亏虚证
分 类 号:R246.9[医药卫生—针灸推拿学]
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