新生儿经鼻高流量氧疗应用指南(2023)  

Guidelines for high-flow nasal cannula oxygen therapy in neonates(2023)

作　　者：黄益 赵静 滑心恬[1,2] 罗可人 史源 林振浪[4] 唐军[1,2] 封志纯 母得志[1,2] 中国医师协会新生儿科医师分会循证专业委员会 HUANG Yi;ZHAO Jing;HUA Xintian;LUO Keren;SHI Yuan;LIN Zhenlang;TANG Jun;FENG Zhichun;MU Dezhi;Evidence-Based Medicine Group,Neonatologist Society,Chinese Medical Doctor Association(Department of Neonatology,West China Second University Hospital,Sichuan University,Chengdu 610041,P.R.China;Key Laboratory of Birth Defects and Related Diseases of Women and Children,Ministry of Education,Chengdu 610041,P.R.China;Department of Neonatology,Children’s Hospital of Chongqing Medical University,Chongqing 400014,P.R.China;The Second Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,P.R.China;Faculty of Pediatrics,the Chinese PLA General Hospital,Beijing 100007,P.R.China;Research Institute of Pediatric Medicine Department,the 7th Medical Center of PLA General Hospital,Beijing 100007,P.R.China;National Engineering Laboratory for Birth Defects Prevention and Control of Key Technology,Beijing 100007,P.R.China;Beijing Key Laboratory of Pediatric Organ Failure,Beijing 100007,P.R.China;不详)

机构地区：[1]四川大学华西第二医院新生儿科,成都610041 [2]出生缺陷与相关妇儿疾病教育部重点实验室,成都610041 [3]重庆医科大学附属儿童医院新生儿科,重庆400014 [4]温州医科大学附属第二医院,浙江温州325000 [5]中国人民解放军总医院儿科医学部,北京100007 [6]中国人民解放军总医院第七医学中心儿科医学部研究所,北京100007 [7]出生缺陷防控关键技术国家工程实验室,北京100007 [8]儿童器官功能衰竭北京市重点实验室,北京100007 [9]不详

出　　处：《中国循证医学杂志》2024年第4期385-404,共20页Chinese Journal of Evidence-based Medicine

基　　金：国家自然科学基金项目(编号:82171710、82271749);国家重点研发计划项目(编号:2021YFC2701700、2021YFC2701704)。

摘　　要：经鼻高流量(HFNC)氧疗,作为重要的无创呼吸支持模式之一,因为其舒适、易于启动、鼻损伤发生率低等优点,越来越多地应用于呼吸衰竭的危重新生儿。其使用优势、适应证及风险等也是近年研究的热点。基于现有证据,本指南采用证据推荐分级评估、制订与评价方法(GRADE),并广泛征求新生儿科医生、呼吸治疗师、护理专家及循证医学等专家意见后制订。本指南针对9个关键问题提出了24条建议,旨在成为临床实践中HFNC氧疗的证据和参考来源,使更多的新生儿及其家庭从HFNC中获益。High-flow nasal cannula(HFNC)oxygen therapy,which is important in noninvasive respiratory support,is increasingly being used in critically ill neonates with respiratory failure because it is comfortable,easy to set up,and has a low incidence of nasal trauma.The advantages,indications,and risks of HFNC have been the focus of research in recent years,resulting in the development of the application.Based on current evidence,we developed guidelines for HFNC in neonates using the grading of recommendations assessment,development and evaluation(GRADE).The guideline was formulated after extensive consultations with neonatologists,respiratory therapists,nurse specialists,and evidence-based medicine experts.We have proposed 24 recommendations for 9 key questions.This guideline aims to be a source of evidence and references of HFNC oxygen therapy in clinical practice,and so that more neonates and their families will benefit from HFNC.

关 键 词：氧气吸入疗法 鼻导管 高流量 指南 新生儿 

分 类 号：R722.1[医药卫生—儿科]