宫颈扩张球囊联合催产素静脉滴注引产的有效性和安全性分析  

Effectiveness of cervical dilation balloon combined with intravenous infusion of oxytocin in inducing labor and security analysis

作　　者：陆文兰 吴朝勇 LU Wen-lan;WU Chao-yong(The First Department of Obstetrics,Keqiao District Maternal and Child Health Care Hospital,Shaoxing,Zhejiang 312030,China)

机构地区：[1]绍兴市柯桥区妇幼保健院产一科,浙江绍兴312030

出　　处：《中国妇幼保健》2024年第8期1383-1386,共4页Maternal and Child Health Care of China

基　　金：浙江省医药卫生科技计划项目(2020ZH060)。

摘　　要：目的探讨宫颈扩张球囊联合催产素静脉滴注引产的有效性和安全性。方法回顾性选取2020年1月—2022年12月绍兴市柯桥区妇幼保健院收治的115例产妇为研究对象,根据患者引产方式的不同分为对照组(53例)和观察组(62例),对照组采用静滴缩宫素引产,观察组采用宫颈扩张球囊联合催产素引产。比较两组引产效果。结果观察组Bishop宫颈评分[(7.31±0.56)分]和宫颈成熟有效率(98.39%)均高于对照组[(6.34±0.29)分、81.13%],差异均有统计学意义(t=11.369,χ^(2)=9.834,均P<0.05)。观察组阴道分娩率(38.71%,24/62)高于对照组(9.43%,5/53),差异有统计学意义(χ^(2)=12.986,P<0.05)。与分娩前相比,两组分娩后血清皮质醇(CORT)、儿茶酚胺(CA)及谷氨酸(GLU)水平均明显降低,观察组血清CORT[(56.29±2.83)μg/L]、CA[(214.62±40.59)ng/L]及GLU[(5.22±0.54)mmol/L]水平均低于对照组[(65.38±2.41)μg/L、(247.73±41.02)ng/L及(7.48±0.61)mmol/L],差异均有统计学意义(t=18.370、4.339及21.073,均P<0.05)。观察组患者的诱发临产时间[(11.84±0.51)h]、第一产程[潜伏期:(4.11±0.71)h,活跃期:(1.03±0.29)h]、第二产程[(0.56±0.09)h]、总产程[(6.34±2.83)h]及住院时间[(3.84±1.52)d]均低于对照组[(18.59±0.42)h、(6.73±1.28)h、(3.21±0.95)h、(0.83±0.18)h、(11.05±1.58)h及(7.79±1.84)d],差异均有统计学意义(t=76.651、13.825、17.168、10.393、10.762及12.606,均P<0.05)。观察组并发症发生率(4.83%)低于对照组(33.96%),差异有统计学意义(χ^(2)=16.237,P<0.05)。结论宫颈扩张球囊联合催产素静脉滴引产能够有效提升引产效果,且安全性较高。Objective To investigate the efficacy and safety of cervical dilatation balloon combined with oxytocin intravenous drip for induction of labor.Methods A total of 115 pregnant women admitted to Keqiao District Maternal and Child Health Care Hospital from January 2020 to December 2022 were retrospectively selected as the research objects.According to the different methods of labor induction,the patients were divided into the control group(53 cases)and the observation group(62 cases).The observation group was treated with cervical dilatation balloon combined with oxytocin induction.The effect of induction of labor was compared between the two groups.Results The Bishop cervical score[(7.31±0.56)points]and the effective rate of cervical ripening(98.39%)in the observation group were higher than those in the control group[(6.34±0.29)points,81.13%],the difference were statistically significant(t=11.369,χ^(2)=9.834,all P<0.05).The rate of vaginal delivery in the observation group(38.71%,24/62)was higher than that in the control group(9.43%,5/53),the difference was statistically significant(χ^(2)=12.986,P<0.05).Compared with before delivery,the levels of serum cortisol(CORT),catecholamine(CA)and glutamate(GLU)in the two groups were significantly decreased after delivery.The serum CORT[(56.29±2.83)μg/L],CA[(214.62±40.59)ng/L]and GLU[(5.22±0.54)mmol/L]in the observation group were lower than those in the control group[(65.38±2.41)μg/L,(247.73±41.02)ng/L and(7.48±0.61)mmol/L],the differences were statistically significant(t=18.370,4.339,and 21.073,all P<0.05).In the observation group,the induced labor time[(11.84±0.51)h],the first stage of labor[incubation period:(4.03±0.29)h,active phase:(1.03±0.29)h],the second stage of labor[(0.56±0.09)h],the total stage of labor[(6.34±2.83)h],hospital stays[(3.84±1.52)d],they were lower than those in the control group[(1.82±0.42)h,(6.73±1.28)h,(3.21±0.95)h,(0.83±0.18)h,(11.05±1.58)h and(7.79±1.58)d],the differences were all statistically significant(t=76.651,13.825

关 键 词：宫颈扩张球囊 催产素 引产效果 安全性 

分 类 号：R725.65[医药卫生—儿科]