单孔法电视辅助胸腔镜肺叶切除术对肺结核患者免疫细胞水平、VAS评分及并发症的影响  

Effects of Uniportal Video-assisted Thoracoscopic Surgery Lobectomy on Immune Cell Levels,VAS Scores and Complications in Patients with Pulmonary Tuberculosis

作　　者：张玉宝 赵宇飞 魏子昂 ZHANG Yubao;ZHAO Yufei;WEI Zi’ang(Department of Cardiothoracic Surgery,Inner Mongolia Fourth Hospital,Hohhot 010010,China;不详)

机构地区：[1]内蒙古自治区第四医院心胸外科,内蒙古呼和浩特010010

出　　处：《中国医学创新》2024年第12期61-65,共5页Medical Innovation of China

摘　　要：目的:分析单孔法电视辅助胸腔镜(uniportal video-assisted thoracoscopic surgery,UVTAS)肺叶切除术对肺结核患者免疫细胞水平、视觉模拟评分法(VAS)评分及并发症的影响。方法:选取2020年1月—2022年1月在内蒙古自治区第四医院接受UVTAS肺叶切除术的100例肺结核患者,随机分为对照组(n=50)和研究组(n=50)。对照组接受双操作孔胸腔镜手术,研究组接受UVTAS肺叶切除术。比较两组免疫细胞水平、VAS评分及并发症的变化。结果:两组免疫细胞水平时间、组间、交互效应比较,差异均有统计学意义(P<0.05)。术后1周,研究组CD3^(+)T淋巴细胞、CD4^(+)T淋巴细胞均显著高于对照组,CD8^(+)T淋巴细胞低于对照组(P<0.05);术后1个月,两组免疫细胞水平,差异均无统计学意义(P>0.05)。术后1周,两组VAS评分均比术后1 d低(P<0.05),且研究组更低(P<0.05)。研究组的术后并发症发生率显著低于对照组(P<0.05)。结论:UVTAS肺叶切除术能够提高肺结核患者的免疫功能,减轻术后疼痛及并发症。Objective:To analyze the effects of uniportal video-assisted thoracoscopic surgery(UVTAS)lobectomy on immune cell levels,visual analogue scale(VAS)scores and complications in patients with pulmonary tuberculosis.Method:A total of 100 pulmonary tuberculosis patients receiving UVTAS lobectomy in Inner Mongolia Fourth Hospital from January 2020 to January 2022 were selected and randomly divided into control group(n=50)and study group(n=50).The control group received thoracoscopic lobectomy with double operating holes,and the study group received UVTAS lobectomy.The immune cell levels,VAS scores and complications between the two groups were compared.Result:There were significant differences in immune cell level time,intergroup and interaction effect between the two groups(P<0.05).1 week after surgery,CD3^(+)T lymphocytes and CD4^(+)T lymphocytes in the study group were significantly higher than those in the control group,and CD8^(+)T lymphocytes was lower than that in the control group(P<0.05);1 month after surgery,there were no significant differences in immune cell levels between the two groups(P>0.05).1 week after surgery,VAS scores in both groups were lower than those 1 day after surgery(P<0.05),and those in the study group were lower(P<0.05).The incidence of postoperative complications in the study group was significantly lower than that in the control group(P<0.05).Conclusion:UVTAS lobectomy can improve the immune function of patients with pulmonary tuberculosis and reduce postoperative pain and complications.

关 键 词：单孔法电视辅助胸腔镜 肺叶切除 肺结核 免疫细胞水平 并发症 

分 类 号：R521[医药卫生—内科学]