儿童轮状病毒胃肠炎免疫预防专家共识(2024年版)  

Expert consensus on immunoprophylaxis of childhood rotavirus gastroenteritis(2024 version)

作　　者：儿童轮状病毒胃肠炎专家共识编写组 段招军[2] 李金松[2] 张静[3] 邓莉[4] 赵鲁卿[5] 李丹地[2] 李静欣[2] Writing Group for Expert Consensus on Rotavirus Gastroenteritis;Duan Zhaojun(不详;Natinal Key Laboratory of Intelligent Tracking and Forecasting for Infection Diseases/NHC Key Laboratory of Medical Virology and Viral Diseases/National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China)

机构地区：[1]不详 [2]传染病溯源预警与智能决策全国重点实验室、国家卫生健康委员会医学病毒与病毒病重点实验室、中国疾病预防控制中心病毒病预防控制所,北京102206 [3]中国疾病预防控制中心 [4]首都儿科研究所 [5]北京中医医院

出　　处：《中华预防医学杂志》2024年第4期421-453,共33页Chinese Journal of Preventive Medicine

摘　　要：轮状病毒胃肠炎(RVGE)是严重威胁5岁以下儿童健康的全球性公共卫生问题。中国RVGE相关疾病负担重,防控难度大。本共识在《儿童轮状病毒胃肠炎免疫预防专家共识(2020版)》和《世界卫生组织轮状病毒疫苗立场文件-2021年7月》的基础上,系统阐述了RVGE流行病学、已上市轮状病毒(RV)疫苗的安全性、有效性和免疫保护持久性、RV疫苗免疫策略等国内外研究进展,增补了常见的RVGE诊疗方案。本共识旨在从预防为主和医防融合的角度出发,推动落实以疫苗接种为重点的RVGE综合性防控措施,降低儿童RVGE疾病负担,为从事疾病预防控制、疫苗接种、临床诊疗等多领域的工作人员提供参考。Rotavirus gastroenteritis(RVGE)is a global public health challenge that seriously threatens the health of children under 5 years of age.In China,the burden associated with RVGE is substantial and its prevention and control are difficult.On the basis of Expert Consensus on Immunoprophylaxis of Childhood Rotavirus Gastroenteritis(2020 Version)and Rotavirus Vaccines and WHO Position Paper-July 2021,this updated consensus systematically reviewed advances in RVGE epidemiological research,safety,effectiveness/efficacy,and immune persistence of post-marketing rotavirus(RV)vaccines,and RV immunization strategies.It also provided guidance for RVGE diagnosis and treatment.Following the principles of prioritizing prevention and integrating medical and preventive approaches,this consensus aims to facilitate the implementation of comprehensive prevention and control measures focusing on RV vaccination to reduce the childhood RVGE disease burden and provide reference for professionals working for disease control and prevention,vaccination,clinical diagnosis and treatment,and related fields.

关 键 词：轮状病毒胃肠炎 轮状病毒疫苗 免疫预防 共识 

分 类 号：R725.1[医药卫生—儿科]