肿瘤患者静脉血栓栓塞症风险评估的最佳证据总结  

Summary of best evidence for risk assessment of venous thromboembolism in cancer patients

作　　者：赵雨婷 张义静[1] 孙丽[1] 范明逗 ZHAO Yuting;ZHANG Yijing;SUN Li;FAN Mingdou(Zhongda Hospital Southeast University,Nanjing Jiangsu 210009)

机构地区：[1]东南大学附属中大医院,江苏南京210009

出　　处：《天津护理》2024年第2期193-197,共5页Tianjin Journal of Nursing

摘　　要：目的:整合肿瘤患者静脉血栓栓塞症(VTE)风险评估的最佳证据,为肿瘤患者静脉血栓栓塞症风险评估管理,降低肿瘤患者静脉血栓栓塞症的发生率提供参考。方法:检索PubMed、循证卫生保健中心数据库、BMJ最佳临床实践、Cochrane Library、英国国家临床医学研究所指南库、美国指南网、Embase、中国知网、万方数据库及中国生物医学文献数据库中所有关于肿瘤患者静脉血栓栓塞症风险评估的证据,包括指南、系统评价、Meta分析、专家共识、最佳临床实践、证据总结及原始研究,检索时间段为2001年8月至2022年8月。由2名经过循证培训的研究人员独立对文献进行筛选、质量评价,形成最佳证据总结。结果:共纳入8篇文献,其中系统评价2篇、指南6篇。从个体因素、肿瘤特征相关因素、肿瘤治疗相关因素、生物标志物4个方面总结了14项最佳证据。结论:对于肿瘤患者进行静脉血栓栓塞症早期风险评估,可以有效预测肿瘤患者静脉血栓栓塞症的发生。医务人员应结合医院的具体管理情况,按照相关级别的循证医学证据建立肿瘤患者静脉血栓栓塞症风险评估的制度、程序和实践标准,提升管理质量。Objective:To evaluate and integrate the best evidence of venous thromboembolism risk assessment in tumor patients,so as to provide reference for reducing the incidence of venous thromboembolism in cancer patients.Methods:All evidence on the risk assessment of venous thromboembolism in cancer patients including guidelines,systematic evaluation,Meta-analysis,expert consensus,best clinical practice,evidence summary and original studies was obtained from PubMed,Evidence-Based Health Care Center Database,BMJ Best Practice,Cochrane Library,the UK National Institute of Clinical Medicine Guidelines,the USA Guidelines,Embase,CNKI,Wanfang Database and the Chinese Medical Biobank.The retrieval time was ranged from August 2001 to August 2022.Results:A total of 8 articles were included,including 2 systematic reviews and 6 guidelines.Four categories of risks including individual factors,tumor characteristic related factors,tumor treatment related factors and biomarkers were summarized with a total of 14 best evidences.Conclusion:Early and comprehensive risk assessment of venous thromboembolism is crucial to the prevention of tumor patient-related thrombosis.Medical staff should establish the system,procedures and practical standards of venous thromboembolism risk assessment of tumor patients according to the specific situation of the hospital and the relevant evidence-based medical evidence,so as to improve the quality of care.

关 键 词：肿瘤 静脉血栓栓塞症 风险评估 循证医学 

分 类 号：R473.73[医药卫生—护理学]