妊娠剧吐患者的营养状况及妊娠结局分析  

Analysis of nutritional status and pregnancy outcome in patients with hyperemesis gravidarum

作　　者：王晶晶 张明[1] 牛琛 齐玉梅 WANG Jingjing;ZHANG Ming;NIU Chen;QI Yumei(Department of Nutriology,the Third Central Hospital of Tianjin,Tianjin 300170,China;Tianjin Key Laboratory of Extracorporeal Life Support for Critical Diseases Artificial Cell Engineering;Artificial Cell Engineering Technology Research Center,Tianjin,China;Tianjin Institute of Hepatobiliary Disease;National Clinical Nutrition Quality Control Center)

机构地区：[1]天津市第三中心医院营养科,300170 [2]天津市重症疾病体外生命支持重点实验室 [3]天津市人工细胞工程技术研究中心 [4]天津市肝胆疾病研究所 [5]国家临床营养质控中心

出　　处：《天津医药》2024年第5期532-535,共4页Tianjin Medical Journal

摘　　要：目的探讨妊娠剧吐(HG)患者的营养状况及其对妊娠结局的影响。方法以153例妊娠剧吐患者及其新生儿为观察组,350例健康产妇及其新生儿为对照组,比较2组孕妇特征和妊娠结局特点。妊娠剧吐患者新生儿中低出生体质量组7例、正常体质量组146例,分析2组孕妇快速反应蛋白、维生素和微量元素水平。结果与对照组比较,观察组新生儿平均出生体质量低,早产率、低出生体质量比例、女婴比例高(P<0.05)。观察组普遍存在微量营养素缺乏,其中维生素D、血清锰、锌缺乏尤为常见。与正常体质量组比较,低出生体质量组孕妇体质量减轻较多,孕期锌、铁、维生素C水平低(P<0.05)。结论HG患者应关注维生素D、锰和锌的补充,新生儿低出生体质量与孕妇孕期体质量下降水平偏高以及孕期锌、铁、维生素C水平偏低有关。Objective To investigate the nutritional status of hyperemesis gravidarum(HG)patients and its influence on pregnancy outcome.Methods A total of 153 cases of HG and their newborns were taken as the observation group,and 350 cases of healthy women and their newborns were used as the control group.The characteristics of pregnant women and pregnancy outcomes were compared between the two groups.In patients with HG,7 newborns were in the low birth weight group and 146 cases in the normal birth weight group.The levels of fast reaction protein,vitamin and trace element were analyzed in the two groups.Results Compared with the control group,the mean birth weight of newborns was lower,the preterm birth rate was higher,the proportion of low birth weight was higher and the probability of female birth was higher in the observation group(P<0.05).Micronutrient deficiency was common in the observation group,especially vitamin D,serum manganese and zinc deficiency.Compared with the normal body weight group,more weight loss and lower levels of zinc,iron and vitamin C during pregnancy in the low birth weight group(P<0.05).Conclusion HG patients should pay attention to the supplementation of vitamin D,manganese,and zinc.Low birth weight of newborns is associated with a higher level of decline in pregnancy body weight and lower levels of zinc,iron,and vitamin C during pregnancy.

关 键 词：妊娠剧吐 营养不良 妊娠结局 婴儿 早产 低出生体质量 

分 类 号：R714.25[医药卫生—妇产科学]