2023年中国肝移植临床研究年度盘点  

Highlights of clinical research on liver transplantation in China of 2023

作　　者：王芳菲 贺强[1] Wang Fangfei;He Qiang(Department of Hepatobiliary Surgery,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China)

机构地区：[1]首都医科大学附属北京朝阳医院肝胆外科,北京100020

出　　处：《器官移植》2024年第3期377-382,共6页Organ Transplantation

基　　金：国家自然科学基金(82370665);北京市自然科学基金(7212042、7222303、7232068);北京朝阳医院金种子科研基金(CYJZ202204)。

摘　　要：肝移植作为成熟的器官移植手术已成为终末期肝病的最佳治疗手段,提高了患者的生存质量。但目前肝移植依然面临诸多挑战,如排斥反应、感染、胆道并发症、移植物功能恢复延迟、缺血-再灌注损伤、肝细胞癌肝移植术后复发、移植后肾相关疾病、供者短缺等,亟待改善和解决。伴随着我国各位专家学者不断的尝试和经验总结,肝移植相关问题逐年突破。2023年,中国肝移植团队在临床研究领域取得了一系列重大进展,本文就2023年度肝移植临床相关的前沿以及肝移植领域的新技术进展进行综述,总结我国2023年在肝移植领域临床研究取得的成果,以期为促进我国肝移植的进一步发展提供新思路。As a mature organ transplantation,liver transplantation has become the optimal treatment for end-stage liver disease,which can improve the quality of life of recipients.However,liver transplantation still faces multiple challenges,such as rejection,infection,biliary complications,delayed graft function,ischemia-reperfusion injury,recurrence of hepatocellular carcinoma after liver transplantation,kidney-related diseases after transplantation,and donor shortage,etc.,which remain to be improved and urgently resolved.With persistent attempts and experience accumulated by Chinese experts and scholars,these problems related to liver transplantation have been gradually resolved year by year.In 2023,liver transplantation teams in China have achieved a series of significant progresses in the field of clinical research.In this article,clinical frontiers and novel technological progresses in the field of liver transplantation in 2023 were reviewed,and the achievements of clinical liver transplantation in China in 2023 were summarized,aiming to provide novel ideas for promoting further development of liver transplantation in China.

关 键 词：肝移植 排斥反应 缺血-再灌注损伤 感染 移植物功能恢复延迟 胆道并发症 肝细胞癌 慢性肾病 

分 类 号：R617[医药卫生—外科学] R575[医药卫生—临床医学]