某三甲医院2020—2022年重症监护病房多重耐药菌目标性监测分析  

Targeted surveillance analysis of multidrug-resistant organisms in intensive care unit of a level-A tertiary hospital from 2020 to 2022

作　　者：梁琼 蒙华莹 李素艳[1] 韦露云 LIANG Qiong;MENG Huaying;LI Suyan;WEI Luyun(Administration Department of Nosocomial Infection,the Second Affiliated Hospital of Guangxi Medical University,Nanning 530007,China;Center for Clinical Medical Research,the Second Affiliated Hospital of Guangxi Medical University,Nanning 530007,China)

机构地区：[1]广西医科大学第二附属医院医院感染管理科,广西南宁530007 [2]广西医科大学第二附属医院临床医学研究中心,广西南宁530007

出　　处：《临床医学研究与实践》2024年第13期48-51,共4页Clinical Research and Practice

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题(No.Z20201496)。

摘　　要：目的分析广西某三甲医院不同类别重症监护病房(ICU)连续3年检出的多重耐药菌(MDRO)分布特征和变化趋势,为医院MDRO的防控策略提供科学依据。方法收集该院不同类别ICU自2020年1月至2022年12月所有住院患者的MDRO检出数据,统计分析MDRO的分布特征和变化趋势。结果该院各类别ICU患者共分离出病原菌1935株,其中MDRO 631株,MDRO总检出率为32.61%。各类别ICU的MDRO检出数量占全院MDRO的44.94%(631/1404);MDRO检出率居前3位的是耐碳青霉烯鲍曼不动杆菌(CRAB)、耐甲氧西林金黄色葡萄球菌(MRSA)、耐碳青霉烯铜绿假单胞菌(CRPA)。MDRO检出标本类型以呼吸道标本为主,其次为血液和体液标本。结论近3年该院ICU MDRO检出率呈先上升后下降的趋势,CRAB、MRSA、CRPA是下一步MDRO目标性监测与防控管理的重点,同时应加强对重点科室的督查和反馈,保证MDRO感染防控措施的有效执行。Objective To analyze the distribution characteristics and changing trend of multidrug-resistant organisms(MDRO)detected in different types of intensive care unit(ICU)of a level-A tertiary hospital in Guangxi for three consecutive years,so as to provide scientific basis for the prevention and control of MDRO in the hospital.Methods The MDRO detection data of all hospitalized patients in different types of ICU of the hospital from January 2020 to December 2022 were collected,and the distribution characteristics and changing trend of MDRO were statistically analyzed.Results A total of 1935 strains of pathogenic bacteria were isolated from all types of ICU patients in the hospital,including 631 strains of MDRO,and the total detection rate of MDRO was 32.61%.The detected number of MDRO in all types of ICU accounted for 44.94%(631/1404)of the MDRO in the whole hospital;the top three MDRO detection rates were carbapenem-resistant Acinetobacter baumannii(CRAB),methicillin-resistant Staphylococcus aureus(MRSA),carbapenem-resistant Pseudomonas aeruginosa(CRPA).The types of specimens detected by MDRO was mainly respiratory specimens,followed by blood and body fluid specimens.Conclusion In the past three years,the detection rate of MDRO in ICU of the hospital has shown a trend of first rising and then declining.CRAB,MRSA and CRPA are the focus of targeted surveillance and prevention and control management of MDRO in the next step.At the same time,supervision and feedback of key departments should be strengthened to ensure the effective implementation of MDRO infection prevention and control measures.

关 键 词：多重耐药菌 重症监护病房 目标性监测 感染 

分 类 号：R378[医药卫生—病原生物学]