基于属性层次模型评价丁苯酞氯化钠注射液临床应用合理性  

Evaluation of the rationality of clinical application of Butylphthalide and Sodium Chloride Injection based on attribute hierarchical model

作　　者：孙丹丹 张掂 过之一 SUN Dandan;ZHANG Dian;GUO Zhiyi(Department of Pharmacy,Bozhou People’s Hospital,Bozhou 236800,China)

机构地区：[1]亳州市人民医院药学部,安徽亳州236800

出　　处：《现代药物与临床》2024年第3期760-765,共6页Drugs & Clinic

摘　　要：目的建立丁苯酞氯化钠注射液合理使用评价标准,为临床合理使用丁苯酞氯化钠注射液提供依据。方法以丁苯酞氯化钠注射液说明书、相关指南为依据制定评价标准,并采用属性层次模型(AHM)对亳州市人民医院2023年1~7月丁苯酞氯化钠注射液的180份出院病历进行评价。结果180例病历都未在医嘱标注滴注时间,疗程不适宜31例(17.22%)、超适应证22例(12.22%)、用药频次不适宜5例(2.78%)、超禁忌证2例(1.1%)和未监测肝肾功能5例(2.78%)。等级优秀病历120例(66.67%)、良好病历32例(17.78%)和合格病历28例(15.55%)。结论亳州市人民医院丁苯酞氯化钠注射液存在不合理问题,需要多部门协作干预整治。基于属性层次模型AHM的药物合理性评价操作简单,对多因素指标评价结果较好,该方法可广泛用于其他药物合理性评价。Objective To establish the evaluation standard for the rational use of Butylphthalide and Sodium Chloride Injection,and provide a basis for rational clinical use of Butylphthalide and Sodium Chloride Injection.Methods The evaluation criteria of Butylphthalide and Sodium Chloride Injection were developed based on the instruction manual and relevant guidelines,and the attribute hierarchical model was used to evaluate 180 discharged medical records of Bozhou People’s Hospital from January to July 2023 for Butylphthalide and Sodium Chloride Injection.Results None of the 180 medical records were labeled with titration time in the medical prescription,inappropriate course of treatment in 31 cases(17.22%),over-indication in 22 cases(12.22%),inappropriate frequency of medication in 5 cases(2.78%),over-contraindications in 2 cases(1.1%),and failure to monitor hepatic and renal functions in 5 cases(2.78%).Grade excellent medical records 120 cases(66.67%),good medical records 32 cases(17.78%)and qualified medical records 28 cases(15.55%).Conclusion There are many unreasonable problems with Butylphthalide and Sodium Chloride Injection in Bozhou People’s Hospital,which require multi-departmental collaborative intervention for remediation.The drug rationality evaluation based on attribute hierarchical model is simple to operate and has better evaluation results for multi-factor indicators,and this method can be widely used for other drug rationality evaluation.

关 键 词：丁苯酞氯化钠注射液 合理性评价 属性层次模型 超适应证 用药频次 滴注时间 

分 类 号：R971[医药卫生—药品]