预塑形聚醚醚酮在额眶鼻区骨纤维异常增殖症手术中的应用效果分析  

Analysis of the application effect of pre-molded polyetheretherketone in surgery for fibrous dysplasia inthefronto-orbito-nasal area

作　　者：徐勇[1] 邱锷[1] 董浩[1] 吴江平[1] 宋贵东 康军[1] Xu Yong;Qiu E;Dong Hao;Wu Jiangping;Song Guidong;Kang Jun(Department of Neurosurgery,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)

机构地区：[1]首都医科大学附属北京同仁医院神经外科,北京100730

出　　处：《中华神经外科杂志》2024年第4期402-405,共4页Chinese Journal of Neurosurgery

基　　金：首都卫生发展科研专项(2020-2-2058)。

摘　　要：目的探讨预塑形聚醚醚酮在额眶鼻区骨纤维异常增殖症治疗中的应用效果。方法回顾性分析2020年1月至2023年1月首都医科大学附属北京同仁医院神经外科收治的12例额眶鼻区骨纤维异常增殖症患者的临床资料。所有患者均手术切除病变骨质,同时使用预塑形聚醚醚酮修补颅骨缺损。3例视神经受压导致视力下降的患者同时行视神经管开放减压。术中鼻窦开放的患者行鼻窦修补重建。所有患者术后均复查眼眶及头颅CT,并于术后3、6、12个月采用门诊及电话问询的方式进行随访,根据患者的外观恢复程度和并发症的发生率评估治疗的效果和安全性。结果12例患者的手术均顺利完成;术中鼻窦开放行重建者8例,术后均无脑脊液漏发生。出院时,患者术前的额部骨质畸形(12/12)及眼球突出(11/11)症状均消失;所有患者的双侧眉弓均对称,外观恢复良好。12例患者的随访时间[M(Q_(1),Q_(3))]为12(6,12)个月。至末次随访,无一例患者发生植入物移位、感染等并发症。结论额眶鼻区骨纤维异常增殖症患者应用预塑形聚醚醚酮修补病变切除术后的骨质缺损,可改善患者的症状,恢复患者的外观,疗效和安全性均较好。Objective To investigate the application effect of pre-molded polyetheretherketone(PEEK)in the management of fibrous dysplasia in the fronto-orbito-nasal region.Methods The clinical data of 12 patients with fibrous dysplasia involving fronto-orbito-nasal region admitted to the Department of Neurosurgery,Beijing Tongren Hospital,Capital Medical University from January 2020 to January 2023 were retrospectively analyzed.All patients underwent surgical resection of the cranial bone lesions and repair of the skull defect with pre-molded PEEK.Three patients with optic nerve compression and vision loss were simultaneously treated with optic canal decompression,and the patients with sinus opening during operation were treated with sinus repair and reconstruction.All patients underwent postoperative orbital and cranial CT,and were followed up at 3,6,and 12 months after surgery by outpatient clinic and telephone inquiries to assess the efficacy and safety of the treatment in terms of the degree of cosmetic recovery and the incidence of complications.Results Surgeries were successfully completed in all 12 patients.Eight patients underwent open sinus reconstruction,and no cerebrospinal fluid leakage occurred after surgery.At the time of discharge,the patients'preoperative symptoms of frontal bony deformity(12/12)and ocular protrusion(11/11)had disappeared.All patients had symmetrical bilateral brow arches with good cosmetic recovery.The follow-up time[M(Q_(1),Q_(3))]for 12 patients was 12(6,12)months.By the final follow-up,none of the cases had complications such as implant displacement or infection.Conclusion The application of pre-molded PEEK in repair of bone defects after lesion resection in patients with fibrous dysplasia in the fronto-orbito-nasal region can improve patients'symptoms and restore their appearance with good efficacy and safety.

关 键 词：颅骨 神经外科手术 骨纤维异常增殖症 聚醚醚酮 额眶鼻区 

分 类 号：R651.1[医药卫生—外科学]