基于中医治未病理论综合干预治疗慢性支气管炎痰湿质患者临床研究  

Clinical effect of comprehensive intervention based on the theory of treating disease on chronic bronchitis patients with phlegm dampness

作　　者：陈嫚嫚[1] 张静[1] 张群[2] CHEN Manman;ZHANG Jing;ZHANG Qun(Department of Preventive Treatment,Jinan Municipal Hospital of Traditional Chinese Medicine,Jinan,Shandong 250012;Department of Pulmonary Disease,Jinan Municipal Hospital of Traditional Chinese Medicine,Jinan,Shandong 250012)

机构地区：[1]山东省济南市中医医院治未病科,山东济南250012 [2]山东省济南市中医医院肺病科,山东济南250012

出　　处：《河北中医》2024年第4期587-590,共4页Hebei Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局中医药标准化项目[编号:SATCM-2015-BZ(367)]。

摘　　要：目的观察基于中医治未病理论综合干预治疗慢性支气管炎(CB)痰湿质患者的临床疗效。方法选择2019年1月至2020年12月收治的92例CB痰湿质患者为研究对象,按照随机数字表法分为2组,对照组46例予西医常规干预治疗,治疗组46例在对照组的基础上予基于中医治未病理论的综合干预治疗。2组均连续干预12周,比较2组治疗前后痰湿质体质量表评分、肺功能指标[包括用力肺活量(FVC)、第1秒用力呼气容积(FEV_(1))及FEV_(1)/FVC]及炎症因子[包括C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)及白细胞介素6(IL-6)]水平变化情况。结果与本组治疗前比较,2组治疗后痰湿质体质量表评分均降低(P<0.05),且治疗组治疗后痰湿质体质量表评分低于对照组(P<0.05)。与本组治疗前比较,2组治疗后肺功能指标FVC、FEV_(1)及FEV_(1)/FVC水平均升高(P<0.05),且治疗组治疗后FVC、FEV_(1)及FEV_(1)/FVC水平均高于对照组(P<0.05)。与本组治疗前比较,2组治疗后炎症因子血清CRP、TNF-α及IL-6水平均降低(P<0.05),且治疗组治疗后血清CRP、TNF-α及IL-6水平均低于对照组(P<0.05)。结论基于中医治未病理论综合干预CB痰湿质患者临床疗效确切,可有效改善患者痰湿质状况,提高肺功能,减轻机体的炎症反应,积极控制病情。Objective To explore the effect of comprehensive intervention based on the theory of treating disease on chronic bronchitis(CB)with phlegm dampness.Methods A total of 92 cases of CB patients with phlegm dampness in our hospital from January 2020 to December 2021 were selected and randomly divided into control group(n=46)and the treatment group(n=46).All patients were given routine Western medicine(RWM),and those in the treatment group were addtionally given comprehensive intervention based on the theory of treating disease.After 12 weeks of intervention,the curative efficacy of the two groups was calculated,the phlegm-dampness constitution scale,lung function indexes(including forced vital capacity[FVC],forced expiratory volume in 1 second[FEV_(1)]and FEV_(1)/FVC),inflammatory factor(including C-reactive protein[CRP],tumor necrosis factor alpha[TNF-α],interleukin-6[IL-6])were included as comparators between groups before and after intervention.Results After intervention,the scores of phlegm-dampness constitution scale in the both groups were significantly lower than those before intervention(P<0.05),especially in the treatment group(P<0.05).The levels of FVC,FEV_(1) and FEV_(1)/FVC in the both groups were significantly higher than those those before intervention(P<0.05),and the increase was more in the treatment group relative to the control group(P<0.05).The levels of CRP,TNF-αand IL-6 in the both groups were significantly lower than those before intervention(P<0.05),and the decrease was more in the treatment group relative to the control group(P<0.05).Conclusion The comprehensive intervention based on the theory of treating disease on CB patients with phlegm-dampness syndrome has a definite clinical effect.It can significantly improve the condition of phlegm-dampness constitution,increase lung function,reduce inflammatory response,and actively control the disease.

关 键 词：慢性支气管炎 治未病论 痰湿质 中医疗法 

分 类 号：R259.622[医药卫生—中西医结合]