新冠疫情前后腹泻患儿轮状病毒感染情况对比分析  

Comparative analysis of rotavirus infection in children with diarrhea before and after COVID-19 outbreak

作　　者：陈芸 彭程 汪宇 赵凤兰[1] 段海燕 CHEN Yun;PENG Cheng;WANG Yu;ZHAO Fenglan;DUAN Haiyan(Department of Pediatrics,The First Affiliated Hospital of Xi'an Medical University,Xi'an 710077,China)

机构地区：[1]西安医学院第一附属医院儿科,西安710077

出　　处：《山东医药》2024年第12期28-31,共4页Shandong Medical Journal

摘　　要：目的对比新冠疫情前后收治的腹泻患儿发生轮状病毒(RV)感染情况。方法选取2017年1月—2022年12月西安医学院第一附属医院收治的腹泻患儿5793例,将2017年1月—2020年1月定义为新冠疫情前,将2020年1月—2022年12月定义为新冠疫情后,比较新冠疫情前后腹泻患儿RV感染率。结果新冠疫情前后腹泻患儿RV感染者分别为881例(25.29%)、587例(25.41%),新冠前后腹泻患儿发生RV感染比较差异无统计学意义(P均>0.05);新冠疫情前后不同性别腹泻患儿RV感染率比较差异无统计学意义(P均>0.05);新冠疫情前腹泻患儿RV感染率较高年龄段依次为≥1岁~<2岁、7~12个月、≥2岁~<3岁,新冠疫情后腹泻患儿RV感染较高年龄段依次为≥1岁~<2岁、≥2岁~<3岁、7~12个月,新冠前后不同年龄段腹泻患儿RV感染比较差异有统计学意义(P均<0.05);新冠疫情前腹泻患儿RV感染高发月份依次为每年12月、1月、11月,新冠疫情后腹泻患儿RV感染高发月份依次为每年1月、12月、2月,新冠前后不同月份腹泻患儿RV感染比较差异有统计学意义(P均<0.05)。结论新冠疫情后腹泻患儿和RV感染人数虽明显减少,但RV感染仍然是儿童腹泻的主要病因;性别不是腹泻患儿发生RV感染的影响因素;腹泻患儿RV感染高发年龄段<3岁婴幼儿;除秋冬季节外春季有可能也会高发RV感染,应警惕非RV高发季节的RV筛查。Objective To analyze and compare the incidence of rotavirus(RV)infection in children with diarrhea before and after the COVID-19 outbreak.Methods A total of 5793 children with diarrhea admitted to the First Affiliated Hospital of Xi'an Medical University from January 2017 to December 2022 were selected.The period from January 2017 to January 2020 was defined as the time before COVID-19 epidemic,and the period from January 2020 to December 2022 was defined as the time after COVID-19 epidemic.RV infection rate of children with diarrhea before and after the COVID-19 outbreak was compared.Results There were 881(25.29%)and 587(25.41%)cases of RV infection in diarrheal children before and after COVID-19 outbreak,respectively.There was no significant difference in RV infection in diarrheal children before and after COVID-19 outbreak(P>0.05).There was no significant difference in RV infection rate in children with diarrhea of different genders before and after COVID-19 outbreak(P>0.05).The age groups with the highest RV infection rate in children with diarrhea before COVID-19 outbreak were≥1 to<2 years old,7 to 12 months old,and≥2 to<3 years old,and the age groups with the highest RV infection rate after COVID-19 outbreak were≥1 to<2 years old,≥2 to<3 years old,and 7 to 12 months old,respectively.There were significant differences in RV infection in children with diarrhea in different ages before and after COVID-19 outbreak(all P<0.05).The months with high incidence of RV infection in children with diarrhea before COVID-19 outbreak were December,January and November each year,and the months with high incidence of RV infection in children with diarrhea after COVID-19 outbreak were January,December and February each year,respectively.There were statistically significant differences in RV infection in children with diarrhea in different months before and after COVID-19 outbreak(all P<0.05).Conclusions Although the number of children with diarrhea and RV infection drops significantly after COVID-19,RV infection is st

关 键 词：腹泻 轮状病毒 轮状病毒感染 性别 年龄 季节 

分 类 号：R183.4[医药卫生—流行病学]