碳材料用于创伤止血的研究进展  

Research Progress of Carbon Materials for Wound Hemostasis

作　　者：史一涵 贺建林 丁晟 杨焜 侯可心 李钒 SHI Yihan;HE Jianlin;DING Sheng;YANG Kun;HOU Kexin;LI Fan(Institute of Medical Support Technology,Academy of Military Sciences,Tianjin 300161,China;No.920 Hospital of Joint Logistics Support Force,Kunming 650032,China)

机构地区：[1]中国人民解放军军事科学院卫勤保障技术研究所,天津300161 [2]联勤保障部队第920医院,昆明650032

出　　处：《材料导报》2024年第9期28-40,共13页Materials Reports

摘　　要：无法控制的出血是导致战现场伤员死亡的重要原因,因此开发能够快速止血且具有一定急需功能(如抗菌)的材料具有重要意义,可有效保护伤员和降低死亡率。目前常用的有机和无机止血材料均存在一定的不足之处,如环境适应性较差、止血性能不稳定以及潜在的毒副作用等。碳材料一般都具有原料广泛、成本低廉、生物相容性良好、表面易修饰等特点,已经在创伤敷料应用中初步显示出较好的发展前景。本文概括了几种传统和新型的典型碳材料在快速止血和其他创伤救治领域的应用情况,总结了碳材料作为止血剂和创伤敷料等的性能、作用机制及相关制备方法,最后对碳材料用于创伤止血提出了建议和展望。碳材料有望成为战现场和院前急救中一种较为理想的创伤止血敷料。Uncontrollable bleeding is an important cause of death of the wounded at the scene of the war,so it is of great significance to develop materials that can quickly stop bleeding and have certain urgently needed functions(such as antibacterial),which can effectively protect the wounded and reduce mortality.At present,the commonly used organic and inorganic hemostatic materials have certain shortcomings,such as poor environmental adaptability,unstable hemostatic properties and potential toxic and side effects.Carbon materials generally have the characteristics of extensive raw materials,low cost,good biocompatibility and easy surface modification,and have preliminarily shown good development prospects in the application of wound dressings.In this paper,the application of several typical carbon materials including traditional and emerging materials in rapid hemostasis and other wound treatment fields is summarized,and the performance,mechanism of action and related preparation methods of carbon materials as hemostatic agents and wound dressings are summarized.Finally,suggestions and prospects are put forward for the application of carbon materials in wound hemostasis.Carbon materials are expected to be an ideal woundhemostatic dressing in war sites and prehospital care.

关 键 词：碳材料 止血 抗菌 创伤敷料 

分 类 号：TB34[一般工业技术—材料科学与工程]