Cronkhite-Canada综合征1例  

A case of Cronkhite-Canada syndrome

作　　者：黄九香[1] 施林林[1] HUANG Jiuxiang;SHI Linlin(The 904th Hospital of the Joint Logistics Support Force of PLA,Wuxi 214000,China)

机构地区：[1]中国人民解放军联勤保障部队第904医院,江苏无锡214000

出　　处：《皮肤性病诊疗学杂志》2024年第4期266-269,共4页Journal of Diagnosis and Therapy on Dermato-venereology

摘　　要：报告Cronkhite-Canada综合征1例。患者男,68岁,因腹痛、腹泻3个月就诊。皮肤科检查:头发弥漫性稀疏,额顶部明显。上下唇部、双手部、双足底可见对称性弥漫性褐色色素沉着,其上多个绿豆大小的点滴状分布的黑色斑疹,趾指甲远端2/3断裂缺如,甲板表面粗糙、凹凸不平无光泽。双上眼睑及小腿出现凹陷性水肿。实验室检查:贫血、低蛋白血症。电子肠镜检查:结肠多发息肉。诊断:Cronkhite-Canada综合征。给予高蛋白等营养支持治疗和对症处理。治疗后贫血及低蛋白血症明显改善,肠息肉暂无复发。目前仍在进一步随访中。A case of Cronkhite-Canada syndrome is reported.A 68-year-old man presented with stomachache and diarrhea for 3 months.The dermatological examination revealed diffuse hair thinning,especially on the frontal region,symmetrical distribution of brown pigmentation covered with green bean-sized maculopapules on the upper and lower lips,hands,and soles.Two-thirds of distal part of the toenails were missing,with rough and uneven dull surface.Pitted edema was observed on the upper eyelids and legs.Laboratory examination showed anemia and hypoproteinemia.Electronic colonoscopy revealed multiple polyps in the colon.Diagnosis:Cronkhite-Canada syndrome.Following high protein nutritional support and symptomatic treatment,anemia and hypoproteinemia were significantly improved.The patient is still under follow-up.

关 键 词：CRONKHITE-CANADA综合征 色素沉着 脱发 甲营养不良 胃肠道息肉 

分 类 号：R597[医药卫生—内科学]