芪苈强心胶囊联合常规西药治疗老年退行性心脏瓣膜病合并心力衰竭的临床效果  

Clinical Effect of Qili Qiangxin Capsule Combined with Routine Western Medicine in Treatment of Senile Degenerative Heart Valve Disease Complicated with Heart Failure

作　　者：刘汉桃 鲁威 汤新美 Liu Hantao;Lu Wei;Tang Xinmei(Department of Internal Medicine,Huishan District Rehabilitation Hospital of Wuxi City,Wuxi 214181,Jiangsu Province,China;Department of Cardiopulmonary Rehabilitation,Huishan District Rehabilitation Hospital of Wuxi City,Wuxi 214181,Jiangsu Province,China)

机构地区：[1]无锡市惠山区康复医院内科,江苏无锡214181 [2]无锡市惠山区康复医院心肺康复科,江苏无锡214181

出　　处：《中国社区医师》2024年第7期65-67,共3页Chinese Community Doctors

摘　　要：目的:探讨芪苈强心胶囊联合常规西药治疗老年退行性心脏瓣膜病合并心力衰竭的临床效果。方法:选取2021年1月—2022年12月无锡市惠山区康复医院收治的80例老年退行性心脏瓣膜病合并心力衰竭患者作为研究对象,按照随机数字表法分为观察组和对照组,各40例。对照组给予常规西药治疗,观察组在对照组基础上采用芪苈强心胶囊治疗,比较两组治疗效果。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P=0.048)。治疗后,两组6 min步行距离长于治疗前,且观察组长于对照组,两组氨基末端脑钠肽前体水平低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组左室射血分数高于治疗前,且观察组高于对照组;两组左室收缩末内径、左室舒张末内径短于治疗前,且观察组短于对照组,差异有统计学意义(P<0.05)。结论:芪苈强心胶囊联合常规西药治疗老年退行性心脏瓣膜病合并心力衰竭的临床效果较好,能缓解症状,改善心脏功能,促进患者恢复。Objective:To explore the clinical effect of Qili Qiangxin Capsules combined with routine western medicine in the treatment of senile degenerative heart valve disease complicated with heart failure.Methods:A total of 80 elderly patients with degenerative heart valve disease and heart failure admitted to Wuxi City Huishan District Rehabilitation Hospital from November 2021 to December 2022 were selected as the study subjects.They were divided into observation group and control group using the random number table method,with 40 patients in each group.The control group received routine western medicine treatment,while the observation group received Qili Qiangxin Capsules on the basis of the control group.The treatment effects of the two groups were compared.Results:The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P=0.048).After treatment,the 6-min walking distance in the two groups was longer than that before treatment,and the distance in the observation group was longer than that in the control group,while the level of N-terminal brain natriuretic peptide precursor in the two groups was lower than that before treatment,and the level in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the left ventricular ejection fraction in the two groups was higher than that before treatment,and this index in the observation group was higher than that in the control group;the left ventricular end-systolic diameter and left ventricular end-diastolic diameter in the two groups were shorter than those before treatment,and these indexes in the observation group were shorter than those in the control group,and the difference was statistically significant(P<0.05).Conclusion:Qili Qiangxin Capsules combined with routine western medicine has good clinical effects in the treatment of senile degenerative heart valve disease complicated with heart failur

关 键 词：芪苈强心胶囊 老年 退行性心脏瓣膜病 心力衰竭 

分 类 号：R542.5[医药卫生—心血管疾病]