重度中暑肠道损伤机制及血液净化对其干预的研究进展  

Research Progress in Mechanism of Intestinal Injury in Severe Heat Stroke and Blood Purification for Intervention

作　　者：常林遇 倪军 张静 CHANG Linyu;NI Jun;ZHANG Jing(Graduate School,Xinxiang Medical University,Xinxiang 453000,China;Department of Hematology and Endocrinology,the 83rd Army Hospital of Chinese PLA,Xinxiang 453000,China)

机构地区：[1]新乡医学院研究生学院,河南新乡453000 [2]陆军第八十三集团军医院血液内分泌科,河南新乡453000

出　　处：《医学综述》2024年第10期1217-1220,1226,共5页Medical Recapitulate

基　　金：军队后勤科研计划项目(CLJ20J026)。

摘　　要：重度中暑是一种因机体核心温度过高而引起的全身炎症反应性疾病,通常会导致多器官功能障碍。肠道组织损伤和功能障碍在重度中暑发病过程中起关键作用,其发病率和病死率较高,因此需要对重度中暑患者进行有效的降温治疗,防止全身炎症反应和多器官功能障碍的发生。血液净化技术已成功用于重度中暑患者的救治,但其对肠道的影响和作用机制目前尚不清楚。未来还需要对重度中暑机体肠道损伤机制和血液净化干预对其肠道功能的影响进行深入研究,为重度中暑患者的治疗提供新思路。Severe heat stroke is a systemic inflammatory response disease caused by the high core temperature of the body,usually leading to multiple organ dysfunction.Numerous studies have shown that intestinal tissue damage and dysfunction have a critical role in the pathogenesis of severe heat stroke.The disease has a high incidence and mortality rate,so effective cooling treatment for severe heatstroke patients is needed to prevent the occurrence of systemic inflammatory response and multiple organ dysfunction.Blood purification technology has been successfully used in the treatment of patients with severe heat stroke,but its effects on the intestine and its mechanism of action are still unclear.In the future,it is also necessary to carry out more in-depth studies on the impact of intestinal injury mechanism and blood purification intervention on the intestinal function of severe heat stroke,so as to provide new ideas for the treatment.

关 键 词：重度中暑 肠道损伤 发病机制 血液净化 干预机制 

分 类 号：R459.5[医药卫生—治疗学] R82[医药卫生—临床医学]