包被γ-氨基丁酸对断奶应激期内羔羊生长性能及相关血液生化指标的影响  

Effect of Encapsulated Gamma-Aminobutyric Acid on Growth Performance and Related Bloodbiochemical Indexes in Lambs during Weaning Stress Period

作　　者：唐亚楠 李炯 魏赜 尹雪姣[1] 刘月琴[1] 张英杰[1] 段春辉[1] TANG Yanan;LI Jiong;WEI Ze;YIN Xuejiao;LIU Yueqin;ZHANG Yingjie;DUAN Chunhui(College of Animal Science and Technology,Hebei Agricultural University,Hebei Baoding 071000,China)

机构地区：[1]河北农业大学动物科技学院,河北保定071000

出　　处：《饲料工业》2024年第9期78-85,共8页Feed Industry

基　　金：国家肉羊产业技术体系项目[CARS-38]。

摘　　要：试验旨在研究日粮中添加不同水平包被γ-氨基丁酸(GABA)对断奶应激期内羔羊生长性能、抗氧化以及神经肽类指标的影响。选择45日龄健康状况良好、体重为(26.14±1.40)kg的湖羊羔羊48只,随机等分为4组,对照组饲喂基础日粮,试验Ⅰ、Ⅱ、Ⅲ组分别在基础日粮中添加100、140、180 mg/d包被GABA,羔羊48日龄断奶(记为第1天),分别记录羔羊采食量及体重,在第-3、1、3、7天采集血液测定相关指标。结果表明:①添加包被GABA显著影响羔羊平均日增重(ADG)(P<0.05),时间显著影响羔羊体重(BW)、ADG和ADFI(P<0.05),添加包被GABA×时间对羔羊生长性能无影响(P>0.05)。②添加包被GABA和时间显著影响羔羊血清抗氧化指标中丙二醛(MDA)含量和谷胱甘肽过氧化物酶(GSH-Px)活性(P<0.05),添加包被GABA降低了MDA含量、升高了GSH-Px水平;随着时间延长,MDA含量、GSH-Px活性呈先增加后降低趋势。③添加包被GABA显著降低了胆囊收缩素(CCK)和神经肽Y(NPY)含量(P<0.05),时间显著影响血清中CCK、NPY水平(P<0.05),随着时间延长CCK水平整体呈增加趋势。④添加包被GABA显著影响血清去甲肾上腺素、五羟色胺、多巴胺含量(P<0.05),添加包被GABA降低了去甲肾上腺素、多巴胺水平,升高了五羟色胺含量;随着时间延长,去甲肾上腺素含量总体呈升高趋势。综上,在日粮中添加包被GABA可通过提高抗氧化能力、降低大脑兴奋性缓解断奶应激,改善生长性能,本试验条件下包被GABA的最佳添加量为140 mg/d。In this study,we investigated the effects of encapsulatedγ-aminobutyric acid(GABA)on weaning stress,growth performance,antioxidation and neuropeptides in lambs.Forty-eight healthy 45 days Hu lambs with similar body weight[(26.14±1.40)kg]were randomly assigned into four groups:the control group(fed basal diet),treatmentⅠgroup(fed basal diet+100 mg/d of GABA),treatmentⅡgroup(fed basal diet+140 mg/d of GABA),and treatmentⅢgroup(fed basal diet+180 mg/d of GABA).All lambs were weaned at 48 days of age(day 1 of experiment).Feed intake(FI)and body weight(BW)of the lambs were recorded during the test period,and blood was collected on-3,1,3,7 d.The results showed that,①added GABA could significantly affect the average daily weight gain of lambs(P<0.05),the time significantly affected the BW,ADG and ADFI of lambs(P<0.05),while added GABA was no difference on the growth performance of lambs(P>0.05).②Added GABA×time had no effect on the growth performance of lambs(P>0.05),and the addition of encapsulated GABA decreased the MDA content and increased the GSH-Px level;time could significantly affect the contents of MDA and GSH-Px in serum(P<0.05)the MDA and GSH-Px contents showed a trend of increasing and then decreasing with the prolongation of time.③Added GABA could significantly reduced the contents of cholecystokinin(CCK)and neuropeptide Y(NPY)(P<0.05);time significantly affected serum CCK and NPY content(P<0.05),as time increased,the overall trend of NPY was increasing.④Added GABA could decreased norepinephrine(NE)and dopamine(DA)levels and elevated pentazocine levels.Norepinephrine levels generally tended to increase with time.In conclusion,the addition of encapsulatedγ-aminobutyric acid to the diets can improve growth performance by increasing the antioxidant capacity and decreasing the excitability of the brain to alleviate weaning stress.The optimal amount of encapsulatedγ-aminobutyric acid was 140 mg/d under the present experimental conditions.

关 键 词：羔羊 断奶应激 Γ-氨基丁酸 生长性能 抗氧化 

分 类 号：S816.7[农业科学—饲料科学]