紫菀药材中33种禁用农药残留分析  

Analysis of 33 Prohibited Pesticide Residues in Asteris Radix Et Rhizoma

作　　者：罗丽娟 周劲松 马恩耀 孙心恒 黄丹虹 刘劲涛 LUO Lijuan;ZHOU Jinsong;MA Enyao;SUN Xinheng;HUANG Danhong;LIU Jintao(Guangdong Hanchao Traditional Chinese Medicine Technology Co.,LTD./Guangdong Traditional Chinese Medicine Innovation Center,Guangzhou Guangdong 510000,China;Guangzhou Caizhilin Pharmaceutical Co.,LTD.,Guangzhou Guangdong 510360,China;Czezhilin〈Meizhou〉Pharmaceutical Co.,LTD.,Meizhou Guangdong 514000,China)

机构地区：[1]广东汉潮中药科技有限公司/广东省传统中药创新中心,广东广州510000 [2]广州采芝林药业有限公司,广东广州510360 [3]广药采芝林〈梅州〉药业有限公司,广东梅州514000

出　　处：《江西化工》2024年第2期25-28,33,共5页Jiangxi Chemical Industry

基　　金：广东省重点领域研发计划(2020B1111120002);广州市荔湾区科技计划项目(202105001);广州市重点研发计划(SL2022B03J01258);广东省传统中药创新中心。

摘　　要：目的:评价紫菀药材中33种禁用农药残留情况。方法:样品用乙腈提取,再经固相萃取柱净化,采用高效液相色谱-串联质谱法和气相色谱-串联质谱法测定33种禁用农药的残留量,外标法定量。结果:线性关系良好,相关系数均大于0.995,加样回收率的范围在70.2%~106.9%。20批的紫菀药材中甲拌磷检出率为100%。结论:所用方法准确、灵敏;紫菀药材生产须关注甲拌磷残留问题。Objective:To evaluate the residues of 33 prohibited pesticides in Asteris radix et rhizoma.Methods:Extracting samples with acetonitrile and cleaning up with solid phase extraction,high performance liquid chromatographytandem mass spectrometry and gas chromatography-tandem mass spectrometry were used to detect the residues of 33 prohibited pesticides in Atractylodes macrocephala rhizoma.Results:The calibration curves of 33 forbidden pesticide residues showed good linearities with correlation coefficients above 0.995.The measured recoveries ranged from 70.2%to 106.9%.The positive detection rate of phorate in the 20 batches of Asteris radix et rhizoma was 100%.Conclusion:The method is accurate and highly sensitive for the confirmation of 33 prohibited pesticide residue.Phorate residues in Asteris radix et rhizoma must be concerned.

关 键 词：紫菀 禁用农药残留 甲拌磷 

分 类 号：R284.1[医药卫生—中药学]