Carcinoembryonic antigen in the diagnosis,treatment,and follow-up of focal liver lesions  

作　　者：Osman Nuri Dilek Dilaraİrem Arslan Kahraman Gökhan Kahraman 

机构地区：[1]Department of Surgery,İzmir Katip Celebi University,School of Medicine,İzmir 35150,Turkey [2]Department of Patology,Merzifon KMP State Hospital,Amasya 5300,Turkey [3]Department of Radiology,Suluova State Hospital,Amasya 5500,Turkey

出　　处：《World Journal of Gastrointestinal Surgery》2024年第4期999-1007,共9页世界胃肠外科杂志（英文版）（电子版）

摘　　要：In this editorial review,we comment on the article published in the recent issue of the World Journal of Gastrointestinal Surgery.Carcinoembryonic antigen(CEA)is a fetal glycoprotein and can be secreted in very small amounts from healthy adults after birth.CEA is widely used not only for diagnostic tumor markers but also importantly for the management of some gastrointestinal tumors.The most common clinical use is surveillance for the monitoring of colorectal carcinoma.However,CEA can become elevated in several malign or benign characterized pathologies.Serum CEA level may vary depending on the location of the lesion,whether it metastasizes or not,and its histopathological characteristics.It has been determined that cases with high preoperative CEA have a more aggressive course and the risk of metastasis to the lymph tissue and liver increases.In this editorial review,we focused on evaluating the role of CEA in clinical practice with a holistic approach,including the diagnostic and prognostic significance of CEA in patients with focal liver lesions,the role of CEA in follow-up after definitive surgery,and also hepatic resection for metastasis,and the management of all patients with raised CEA.

关 键 词：Carcinoembriyonic antigen LIVER Focal liver lesions METASTASIS Surgery PROGNOSIS SURVEILLANCE 

分 类 号：R735[医药卫生—肿瘤]