益气温阳方治疗变应性鼻炎临床疗效Meta分析  

Meta-analysis on the clinical efficacy of Yiqi Wenyang Decoction in the treatment of allergic rhinitis

作　　者：杨祁 安静娟 杨焕 张彩名 Yang Qi;An Jingjuan;Yang Huan;Zhang Caiming(Second Affiliated Hospital of Nanjing University of Traditional Chinese Medicine(Jiangsu Province Second Hospital of TCM),Department of Otorhinolaryngology,Naijing,Jiansu,210017;Nanjing Jianye District Nanyuan Community Health Service Center,Naijing,Jiansu,210019)

机构地区：[1]南京中医药大学第二附属医院(江苏省第二中医院)耳鼻咽喉科,江苏南京210017 [2]南京市建邺区南苑社区卫生服务中心五官科,江苏南京210019

出　　处：《中医眼耳鼻喉杂志》2024年第2期79-82,共4页Journal of Chinese Ophthalmology and Otorhinolaryngology

基　　金：江苏省第二中医院2023“中青年科技菁英”项目(项目编号:SEZJJZ2023017);2023年度南京中医药大学自然科学基金项目(项目编号:XZR2023066);江苏省中医药科技发展计划项目(项目号MS2022040)。

摘　　要：目的系统全面地评价益气温阳方治疗变应性鼻炎的临床效果。方法利用个人计算机查询CNKI、万方、维普、Pubmed、Web of science数据库中的资料,再利NoteExpress软件对资料进行整理和筛选,使用Review Manager5.3软件对数据进行Meta分析。检索时间:数据库建库至今。纳入益气温阳方治疗变应性鼻炎临床疗效的随机对照试验,对纳入文献的总有效率、症状总评分(TNSS)、嗜酸性粒细胞(EOS)表达水平进行Meta分析。结果总共纳入5篇益气温阳方治疗变应性鼻炎的随机对照试验。益气温阳方治疗变应性鼻炎的总有效率[OR=5.25,95%CI:(2.98,9.24),P<0.00001]、症状总评分[MD=-1.51,95%CI:(-2.01,-1.01),P<0.00001]、嗜酸性粒细胞表达水平[MD=-5.12,95%CI:(-13.86,3.62),P=0.25]。结论益气温阳方能够改善变应性鼻炎患者的临床症状,提高治疗总有效率,具有更好的临床疗效。Objective To systematically and comprehensively evaluate the clinical effect of Yiqi Wenyang Decoction in the treatment of allergic rhinitis.Methods Using personal computer to query the data in CNKI,Wanfang,VIP,Pubmed,Web of science and other databases,and then using NoteExpress software to sort out and screen the data,and using Review Manager 5.3 software for Meta analysis of the data.Retrieval time:database construction so far.A randomized controlled trial was included to evaluate the clinical efficacy of Yiqi Wenyang Decoction in the treatment of allergic rhinitis.Meta-analysis was performed on the total effective rate,total symptom score(TNSS)and eosinophil(EOS)expression level in the included literature.Results A total of five randomized controlled trials were included in this study.The total effective rate of Yiqi Wenyang Decoction in the treatment of allergic rhinitis[OR=5.25,95%CI:(2.98,9.24),P<0.00001],total symptom score[MD=-1.51,95%CI:(-2.01,-1.01),P<0.00001],eosinophil expression level[MD=-5.12,95%CI:(-13.86,3.62),P=0.25].Conclusion Yiqi Wenyang Decoction can improve the clinical symptoms of patients with allergic rhinitis,and the total effective rate of treatment,which has better clinical curative effect.

关 键 词：益气温阳方 变应性鼻炎 临床疗效 META分析 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]