酰基缩氨基脲类化合物的合成及杀虫活性研究  

Study on Synthesis and Insecticidal Activity of Acylaminourea Compounds

作　　者：姜硕 朱宝玉 张如松 光明甲 王明慧[1] 许良忠[1] JIANG Shuo;ZHU Baoyu;ZHANG Rusong;GUANG Mingjia;WANG Minghui;XV Liangzhong(College of Chemistry and Molecular Engineering,Qingdao University of Science&Technology,Qingdao Shandong 266042,China)

机构地区：[1]青岛科技大学化学与分子工程学院,山东青岛266042

出　　处：《辽宁化工》2024年第4期514-517,共4页Liaoning Chemical Industry

摘　　要：为获得高活性杀虫剂,以氰氟虫腙为先导化合物,通过中间体衍生化法合成了8个未见文献报道的酰基缩氨基脲类化合物,对其结构进行^(1)H NMR、^(13)C NMR、HRMS表征,并对化合物进行杀虫活性测试。结果表明:在质量浓度为50 mg·L^(-1)时候,多数化合物对棉蚜都有一定的杀虫活性,其中Ⅰ-5a、Ⅰ-5d、Ⅰ-5e生物活性最高,高达100%。降低生测质量浓度后,在10 mg·L^(-1)时,活性最好的Ⅰ-5e能够达到76%。由于本系列化合物结构新颖、杀虫效果较好,作为杀虫剂具有研究价值。To obtain highly active insecticides,with cyanflufenazone as the lead compound,8 acyl aminourea compounds were synthesized by intermediate derivatization method,and the synthesized target compounds were characterized by ^(1)H NMR,^(13)C NMR and HRMS,the structure of all target compounds was determined,and the insecticidal activity test was carried out.The test results showed that for cotton aphid larvae,at a mass concentration of 50 mg·L^(-1),most of the compounds had certain biological activity on gossyroid,among which I-5a,I-5d,I-5e had the highest biological activity,up to 100%.After reducing the bioassay mass concentration,the best activity I.-5e could reach 76%at 10 mg·L^(-1),having research value as an insecticide.

关 键 词：氰氟虫腙 酰基缩氨基脲 有机合成 杀虫活性 

分 类 号：S482.37[农业科学—农药学]