芪红散结合西医常规治疗老年冠心病稳定型心绞痛气虚血瘀证的疗效及生活质量评价  

Qi Hong Powder Combined with Conventional Western Medicine in the Treatment of Elderly Patients with Stable Angina Pectoris of Qi Deficiency and Blood Stasis Syndrome Efficacy and Quality of Life Evaluation

作　　者：曹宇 高伟[1] 黄浩[1] 王晓峰[1] CAO Yu;GAO Wei;HUANG Hao;WANG Xiaofeng(Affiliated Hospital of Traditional Chinese Medicine of Xinjiang Medical,University Urumqi 830000,China)

机构地区：[1]新疆医科大学附属中医医院,乌鲁木齐市830000

出　　处：《中医药临床杂志》2024年第4期741-745,共5页Clinical Journal of Traditional Chinese Medicine

基　　金：国家中医药管理局国家中医临床研究基地业务建设科研专项(编号:JDZX2015011)。

摘　　要：目的:观察芪红散结合西医常规治疗的中西医结合疗法对老年冠心病稳定型心绞痛气虚血瘀证患者临床症状及生活质量的影响,为临床用药提供参考。方法:将72例老年冠心病稳定心绞痛气虚血瘀证病人根据随机信封分成试验组及对照组,各36例,分别予基础治疗加芪红散和基础治疗连续2个月并于治疗后随访12周。比较两组患者心绞痛症状、中医证候评分、西雅图心绞痛评分、欧洲五维健康量表(EQ-5D)评分。结果:(1)心绞痛疗效试验组总有效率80.0%,显著高于对照组的总有效率51.5%(P<0.05),且心绞痛症状积分改善程度明显优于对照组(P<0.05);(2)中医证候疗效试验组总有效率86.6%,显著高于对照组的总有效率60.6%(P<0.05),试验组患者胸痛症状及中医证候积分改善明显优于对照组(P<0.05);(3)EQ-5D评分试验组患者MOB、PA维度困难程度改善明显,且治疗后EQ-5D总评分、EQ-VAS评分及停药12周EQ-VAS评分较前改善均优于对照组(P<0.05,P<0.01)。结论:芪红散结合西医常规治疗老年CAS可明显减轻临床症状,提高患者生活质量,尤其在改善患者躯体活动能力、舒适度方面疗效显著,且安全、有效。Objective:To observe the effect of Qihong Powder combined with conventional Western medicine therapy on the clinical symptoms and quality of life of elderly patients with stable coronary heart disease,angina pectoris,Qi deficiency and blood stasis syndrome,and provide reference for clinical medication.Methods:72 elderly patients with stable coronary heart disease,angina pectoris,Qi deficiency and blood stasis syndrome were divided into experimental group and control group according to random envelopes,with 36 cases in each group.They were given basic treatment plus Qihong Powder and basic treatment for 2 months respectively,and were followed up for 12 months after treatment.week.The angina pectoris symptoms,TCM syndrome scores,SAQ scores,and EQ-5D scores of the two groups were compared.Results:①The total effective rate of the angina pectoris test group was 80.0%,which was significantly higher than the total effective rate of 51.5%in the control group(P<0.05),and the improvement of angina pectoris symptom score was significantly better than that of the control group(P<0.05);②Traditional Chinese Medicine syndrome The total effective rate of the experimental group was 86.6%,which was significantly higher than the total effective rate of 60.6%in the control group(P<0.05).The improvement of chest pain symptoms and TCM syndrome scores of patients in the experimental group was significantly better than that of the control group(P<0.05);③The difficulty level of MOB and PA dimensions of patients in the EQ-5D score test group improved significantly,and the EQ-5D total score,EQ-VAS score after treatment,and the EQ-VAS score after 12 weeks of drug withdrawal were all better than those in the control group(P<0.05,P<0.01).Conclusion:Qihong Powder combined with conventional Western medicine can significantly reduce clinical symptoms and improve patients’quality of life in the treatment of elderly CAS.It is particularly effective in improving patients’physical activity and comfort,and is safe and effective.

关 键 词：芪红散 老年冠心病 稳定型心绞痛 临床疗效 

分 类 号：R541.4[医药卫生—心血管疾病]