过渡金属催化羰基化反应的最新研究进展  

Recent progress in transition metal-catalyzed carbonylation reactions

作　　者：徐山梅 高帆 孙国庆 李明 权正军[1] XU Shan-mei;GAOFan;SUN Guo-qing;LI Ming;QUAN Zheng-jun(Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials,College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070,Gansu,China)

机构地区：[1]保水化学功能材料甘肃省国际科技合作基地,西北师范大学化学化工学院,甘肃兰州730070

出　　处：《西北师范大学学报（自然科学版）》2024年第3期5-24,共20页Journal of Northwest Normal University(Natural Science)

基　　金：国家自然科学基金资助项目(22061038,22067018);甘肃省博士后基金资助项目(00245);西北师范大学学科建设基金资助项目(202103101413,202303101410)。

摘　　要：过渡金属催化羰基化反应是制备羰基化合物最直接的方法之一,近年来得到了迅速的发展.利用活性高且廉价的CO气体作羰基源,通过过渡金属催化的方法实现羰基化,是现代有机合成中构建含羰基化合物的有效方法.基于反应原料和产品氧化还原价态的改变等不同方式,将过渡金属催化羰基化反应分为四种主要类型:杂核亲核试剂的羰基化反应,碳亲核试剂的羰基化反应,碳亲电试剂的羰基化反应和还原偶联的羰基化反应,分别综述了各类型羰基化反应的最新研究进展.Transition metal catalyzed carbonylation reaction is one of the most direct methods for the preparation of carbonyl compounds,which has been developed rapidly in recent years.The use of highly active and inexpensive COgas as a carbonyl source tOrealize carbonylation via transition metal-catalyzed methods is the most effective strategy for atomically economical construction of carbonyl compounds in modern organic synthesis.Herein,the transition metal-catalyzed carbonylation reactions reported in recent years are classified as intOfour categories based on the oxidation-reduction valence state change of the reactant material and product,that is,carbonylation reaction of heteronuclear nucleophiles,carbonylation of carbon nucleophiles,carbonylation reaction of carbon electrophiles,and reductive coupling carbonylation.

关 键 词：过渡金属催化 一氧化碳(CO) 羰基化反应 交叉偶联 还原偶联 

分 类 号：O621.3[理学—有机化学]