基于Neo4j的张道宗针刺治疗原发性头痛证治规律研究  

Study on the syndrome and treatment rules of Zhang Daozong acupuncture for primary headache based on Neo4j

作　　者：徐玉莹 王涛[2] 李佩芳[2] 韩永升 吴子建[4] 贾世震 方培钢 李莹莹 孙鹤天 张道宗[2] Xu Yuying;Wang Tao;Li Peifang;Han Yongsheng;Wu Zijian;Jia Shizhen;Fang Peigang;Li Yingying;Sun Hetian;Zhang Daozong(Graduate School,Anhui University of Chinese Medicine,Hefei 230038,Anhui,China;The Second Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230061,Anhui,China;Wannan Medical College,Wuhu 241002,Anhui,China;Anhui University of Chinese Medicine,Hefei 230012,Anhui,China)

机构地区：[1]安徽中医药大学研究生院,安徽合肥230038 [2]安徽中医药大学第二附属医院,安徽合肥230061 [3]皖南医学院,安徽芜湖241002 [4]安徽中医药大学,安徽合肥230012

出　　处：《右江民族医学院学报》2024年第2期238-245,共8页Journal of Youjiang Medical University for Nationalities

基　　金：国家自然科学基金面上项目(82274656);安徽中医药大学第二附属医院人才支持计划(杏林计划)(0500-48-19);安徽省高校科学研究项目自然科学类(2023AH050844)。

摘　　要：目的探讨基于Neo4j的知识图谱总结张道宗针刺治疗原发性头痛的证治规律。方法收集于2020年至2022年在安徽中医药大学第二附属医院就诊的251例头痛患者临床医案,采用PHP语言、Gephi对取穴进行分析,并运用古今医案云平台进行社团分析,使用PHP 5.6程序代码将支持度≥0.08,置信度为≥0.65的证型、症状、舌象、脉象、取穴转译为Cypher语句,录入Neo4j中。结果针刺取穴多为督脉,占比26.95%,核心处方为百会、太阳、风府、印堂、哑门、头维、风池;置信度≥0.65的证型与取穴:足三里、脾俞→血虚头痛,丰隆→痰浊头痛、风湿头痛,太冲、侠溪→肝阳头痛,风门→风寒头痛,太冲、血海、阿是穴、膈俞→淤血头痛,曲池→风热头痛,肾俞→肾虚头痛;构建“证型-症状-取穴”本体及其间关系的知识图谱模型。结论张道宗针刺治疗原发性头痛以头部、督脉腧穴为主,形成了以“通督脉以和阴阳、启神机以调神志”为主要治则的选穴规律;也表明知识图谱在总结名老中医经验中具有数据整合、知识表达、智能检索等优势。Objective To explore the advantages of knowledge graphs and the presentation of syndrome and treatment rules of acupuncture treatment for headaches by TCM veteran doctors named Zhang Daozong based on Neo4j graph database technology.Methods A total of 251 clinical cases of headache patients treated at the Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine from 2020 to 2022 were analyzed using PHP language,Gephi,and a cloud platform for community analysis.The syndrome types,symptoms,tongue signs,pulse signs,and acupoint selections with a support degree of≥0.08 and a confidence level of≥0.65 were translated into Cypher statements using PHP 5.6 program code,and then inputtedinto Neo4j.Results The main acupuncture point selection was the Governor meridian,accounting for 26.95%.The core acupuncture point prescriptions were Baihui(DU 20),Taiyang(EX-HN 5),Fengfu(GV 16),Yintang(EX-HN 3),Yamen(GV 15),Touwei(ST 8),and Fengchi(GB 20).The relationship between syndrome type and acupuncture point selection with a confidence level≥0.65 included Zusanli(ST 36),Pishu(BL 20)→Xuexu headache,Fenglong(ST 40)→Tanzhuo and Fengshi headache,Taichong(LR 3),Xiaxi(GB 43)→Ganyang headache,Fengmen(BL 12)→Fenghan headache,Taichong(LR 3),Xuehai(SP 10),Ashi point,Geshu(BL 17)→Yuxue headache,Quchi(LI 11)→Fengre headache,Shenshu(BL 23)→Shenxu headache.A knowledge map model of“syndrome type-symptom-acupoint selection”ontology and its relationships were constructed.Conclusion In Zhang Daozong’s acupuncture treatment of headaches,the acupoints on the head are the main focus,and the acupoints on the Governor’s veins are the core,forming an acupoint selection rule with“dredging the Governor’s veins to adjust Yin and Yang,and regulating consciousness”as the main treatment principles.It is demonstrated that knowledge graphs have the advantages of data integration,knowledge representation,and intelligent retrieval in summarizing the experience of TCM veteran doctors.

关 键 词：原发性头痛 针刺 Neo4j 证治规律 知识图谱 

分 类 号：R246.6[医药卫生—针灸推拿学]