胰岛素不同使用方式对小儿糖尿病患儿血糖水平的影响  

Effects of Different Insulin Use Modes on Blood Glucose Levels in Children with Diabetes

作　　者：叶秀玉[1] 颜惠萍 李艺霞 YE Xiuyu;YAN Huiping;LI Yixia(Jinjiang Hospital(Shanghai Sixth Hospital Fujian Hospital),Jinjiang,Fujian Province,362200 China;Quanzhou Maternal and Child Health Hospital Children's Hospital,Quanzhou,Fujian Province,362000 China)

机构地区：[1]福建省晋江市医院(上海六院福建医院),福建晋江362200 [2]泉州市妇幼保健院儿童医院,福建泉州362000

出　　处：《糖尿病新世界》2024年第4期71-74,共4页Diabetes New World Magazine

摘　　要：目的分析胰岛素不同使用方式对小儿糖尿病患儿血糖水平的影响。方法回顾性选取2021年1月—2023年12月福建省晋江市医院收治的40例小儿糖尿病患儿的临床资料,根据不同治疗方式分为参照组(n=20,胰岛素多次皮下注射治疗)、观察组(n=20,胰岛素泵输注治疗),对比两组患儿血清炎性因子水平、血糖水平、临床指标。结果治疗前,两组血清炎性因子水平、血糖水平对比,差异无统计学意义(P均>0.05);治疗后,观察组的血清炎性因子水平、血糖水平低于参照组,差异有统计学意义(P均<0.05)。与参照组的临床指标对比,观察组胰岛素用量更少、餐后2 h血糖水平达标时间更早、住院时间更短,差异有统计学意义(P均<0.05)。两组临床治疗总有效率对比,差异无统计学意义(χ^(2)=2.057,P>0.05)。结论小儿糖尿病患儿治疗中选择胰岛素泵输注治疗,可降低患儿炎性因子水平,减少胰岛素用量,促使患儿血糖水平达标的同时,缩短住院时间,改善患儿血糖水平。Objective To analyze the effect of different ways of insulin use on blood glucose level in children with dia⁃betes.Methods Retrospectively selected the clinical data of 40 cases of pediatric diabetes mellitus children admitted to Jinjiang Hospital in Fujian Province from January 2021 to December 2023 According to the different treatment mo⁃dality,they were divided into the reference group(n=20,insulin multiple subcutaneous injections treatment)and the observation group(n=20,insulin pump infusion treatment).The serum inflammatory factor levels,blood glucose levels,and clinical indicators between two groups of pediatric patients were compared.Results Comparison of serum inflam⁃matory factor levels and blood glucose levels between the two groups before treatment,and the differences were not statistically significant(both P>0.05);after treatment,the serum inflammatory factor levels and blood glucose levels of the observation group were lower than those of the reference group,and the differences were statistically significant(both P<0.05).Compared with the clinical indicators of the reference group,the observation group used less insulin,reached the 2 h postprandial blood glucose level earlier,and had a shorter hospitalization time,and the differences were statistically significant(all P<0.05).Compared with the total effective rate of clinical treatment of the two groups,the difference was not statistically significant(χ^(2)=2.057,P>0.05).Conclusion In the treatment of children with diabe⁃tes,the choice of insulin pump infusion can reduce the level of inflammatory factors in children,reduce the amount of insulin,promote the blood glucose level of children to reach the standard,shorten the hospital stay,and significantly improve the blood glucose level of children.

关 键 词：小儿糖尿病 胰岛素泵输注 胰岛素多次皮下注射 血糖水平 炎性因子水平 不良反应 

分 类 号：R587.1[医药卫生—内分泌]